Conserved Protein Domain Family
PHD_PHF21B
?
cd15524: PHD_PHF21B 
PHD finger found in PHD finger protein 21B (PHF21B)
PHF21B is a plant homeodomain (PHD) finger-containing protein whose biological function remains unclear. It shows high sequence similarity with PHF21A, which is associated with LSD1, a lysine (K)-specific histone demethylase and inhibits LSD1-mediated histone demethylation in vitro. PHD fingers can recognize the unmodified and modified histone H3 tail, and some have been found to interact with non-histone proteins.
Links
?
Statistics
?
PSSM-Id: 276999
Aligned: 4 rows
Threshold Bit Score: 93.419
Created: 14-Aug-2013
Updated: 2-Oct-2020
Structure
?
Aligned Rows:
Download Cn3D
Conserved Features/SitesClick to see Conserved Features Help
 
Zn binding siteputative
Feature 1: Zn binding site [ion binding site], 8 residue positions
Conserved feature residue pattern:C C C [CH] H [CH] C [CH]Click to see conserved feature residue pattern help
Evidence:
Scroll to Sequence Alignment Display
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
Feature 1         #  #        #  #    #  #              #  #
Q96EK2       354 HCAACKRGANLQPCGTCPGAYHLSCLEPPLKtaPKGVWVCPRC 396 human
XP_002942113 442 YCSACKRGSNLQTCGACPRAYHLDCVDPPLKvlPKGVWLCPKC 484 western clawed frog
XP_004938095 317 YCTACKRGVNLQPCGTCPRAYHLNCLDPPLKtaPKGVWVCPKC 359 chicken
XP_006633723 404 HCAVCKERGELQRCHSCPRAYHPDCLDTPLKtpPKGVWVCPKC 446 spotted gar

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap