Conserved Protein Domain Family
PHD_ATX3_4_5_like
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cd15495: PHD_ATX3_4_5_like 
PHD finger found in Arabidopsis thaliana histone-lysine N-methyltransferase arabidopsis trithorax-like protein ATX3, ATX4, ATX5, and similar proteins
The family includes A. thaliana ATX3 (also termed protein SET domain group 14, or trithorax-homolog protein 3), ATX4 (also termed protein SET domain group 16, or trithorax-homolog protein 4) and ATX5 (also termed protein SET domain group 29, or trithorax-homolog protein 5), which belong to the histone-lysine methyltransferase family. They show distinct phylogenetic origins from the ATX1 and ATX2 family. They are multi-domain containing proteins that consist of an N-terminal PWWP domain, a canonical Cys4HisCys3 plant homeodomain (PHD) finger, a non-canonical extended PHD (ePHD) finger, Cys2HisCys5HisCys2His, and a C-terminal SET domain; this model corresponds to the Cys4HisCys3 canonical PHD finger.
Links
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Statistics
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PSSM-Id: 276970
Aligned: 12 rows
Threshold Bit Score: 68.5552
Created: 30-Aug-2013
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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Zn binding siteputative
Feature 1: Zn binding site [ion binding site], 8 residue positions
Conserved feature residue pattern:C C C [CH] H [CH] C [CH]Click to see conserved feature residue pattern help
Evidence:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1          #  #              #    #    #  #                     #  #
Q9M364        548 RCAVCRWVEDWEe-NKMIICN--RCQVAVHQECYGVSKs--------qDLTSWVCRAC 594  thale cress
XP_001777592  468 RCAVCRMVEDWHh-NKMIICN--RCQIAVHEECYGVRAs--------dSVGSWVCRAC 514  Physcomitrella patens subsp. patens
CCO17344      793 RCAVCDDERDFDf-DQLITCE--GCQVSVHQSCYGVHEip-------dQAVGWLCRAC 840  Bathycoccus prasinos
XP_001703016  795 RCSVCDSEIDADs-DRLVSCD--CCGITVHQICYGITEap-------gLDEMWLCRAC 842  Chlamydomonas reinhardtii
EMT28249      218 KCDVCCLGESDAasNRMLQCN--RCKVSVHQKCYGVQVe---------PDGYWMCALC 264  Aegilops tauschii
EAS03088      880 RCQVCNECDYADn-DLIVFCS--RCNMSVHQKCYGIASl---------PQEDWICDAC 925  Tetrahymena thermophila SB210
XP_001767886 1482 DCCVCNEGENDKn-NPVYTCK--NCFMHVHQSCYGIREkfrndqgrifAPPNWFCRIC 1536 Physcomitrella patens subsp. patens
ADN34162      272 LCHFCSKGDTDKglNPLVTCS--FCHVVVHYKCYGIREk---------VNGSWSCSWC 318  Cucumis melo subsp. melo
XP_001433038  236 NCQICNQGVRSE--DPLISCQ--KCQIIVHQKCYGLEN----------AINNWICDVC 279  Paramecium tetraurelia strain d4-2
XP_003382717    4 SCCVCSDGKETTe-NRLFRCGgsGCGIIVHQACYGIVSv---------PSGVWFCRKC 51   Amphimedon queenslandica
Q9SUE7        594 RCAVCRWVEDWDy-NKIIICN--RCQIAVHQECYGARHv--------rDFTSWVCKAC 640  thale cress
Q8GZ42        609 RCAVCRWVEDWDy-NKIIICN--RCQIAVHQECYGTRNv--------rDFTSWVCKAC 655  thale cress

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