Conserved Protein Domain Family
uS7_Mitochondria_Fungi

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cd14868: uS7_Mitochondria_Fungi 
Fungal Mitochondrial homolog of Ribosomal Protein S7
uS7, also known as Ribosomal protein (RP)S7, is an important part of the translation process which is universally present in the small subunit of prokaryotic and eukaryotic ribosomes. Fungal and plants mitochondrial RPS7 shows less homology to the mammalian than to bacterial RPS7. The ribosome small subunit is one of the two subunits of ribosome organelles that use mRNA as a template for protein synthesis in a process called translation. The small subunits of bacteria and eukaryotes have the same shape of head, body, platform, beak, and shoulder. RPS7 is located at the head of the small subunit. RPS7 is a primary ribosomal RNA (rRNA) binding protein that assists in rRNA folding and the binding of other proteins during small subunit assembly in all species. RPS7 is also involved in the formation of the mRNA exit channel at the interface of the large and small subunits. Some ribosomal proteins have extra ribosomal functions in cell differentiation and apoptosis.
Statistics
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PSSM-Id: 271247
Aligned: 48 rows
Threshold Bit Score: 163.898
Created: 26-Nov-2013
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
Feature 1:rRNA binding site [nucleic acid binding site]
Evidence:
  • Comment:Ribosomal protein S7 directly interacts with rRNA during the assembly of small ribosomal subunit.
  • Comment:Ribosomal protein S7 plays a critical role in controlling of rRNA folding.

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                     ###   #####  ##                    
CCM01191      68 RLHNSNAPPVi--------------------nIPPPEDPLLSYFTSCIQKHGNRQKAAGITSRMLLHIHTMTRa--QPLP 125 Fibroporia radi...
ESA20603     207 STEADATTKLtidk---------------ndpRFIREDPVISQAVNIIMRHGKKATARRFLADAMVEIRRQTHn--DPYL 269 Rhizophagus irr...
NP_594222     90 IEVENEEPPLmgtnlwpsp----sssivglidRPFQVDSTVQHLVNLIMRDGKKAKAEKIVATALSIIQKETGe--NPID 163 Schizosaccharom...
XP_002171791  93 PVEEKDTPPNlrasee----------nykqyaKDYNSDEVVSQLVNTIMRHGKKATAQKYVNKALLIVQRELNq--NPVK 160 Schizosaccharom...
EIF47558      89 VAKLLRLNPSxqqkqea--------eeildlpLPSHKDEVLELCVNLIMKNGKKDQARKFVNRALYLIYLKTRs--NPVD 158 Dekkera bruxell...
P47150        82 SQAGSKIKPTaeqlaqw--------ealksvpIPPRKNATLDHITNMIMRHGKKEKAQTILSRALYLVYCQTRq--DPIQ 151 baker's yeast
XP_002489741  81 DTSHLQWQPTqeqleqi--------aelkskpIPLKNDPLIEHCTNLIMKDGLKYKANQYLSKALYLVFLQKRk--DPVE 150 Pichia pastoris...
CCG82469      80 IRQASGDDPTgasts------------vkfkyELPGSDSVLTHLVGVIMKDGKKSQAQSRIQGTLELLQRATQq--DPLA 145 Taphrina deform...
EGF83811      23 PSAALAHNPSngsiqnqlsaedldgevklsevNVKKEHPVIEQFVNNIMKSGNKAVARRIMSDAMLYIQTQTRq--DPRS 100 Batrachochytriu...
EIE83132       7 KSFCQSATPLfrsttvwv------ramstanvTVVPKDDVISQLVNTIMRDGKKARAQRLVSDSMKHLSKKVGeekDPYT 80  Rhizopus oryzae...
Feature 1                       #         #        ##  #   #      #      ##  #                   
CCM01191     126 IVRKAIENVAPAVRCISNKH-AGKTVVYPVALSEKQRTRYAIQWILKASESKPGM-KLEERLAKEIIAAVQSAreersdr 203 Fibroporia radi...
ESA20603     270 ITKAAIEKASPLVSHMSYKK-GSKVTLIPKALNERQRRHKGIRWILDASDKRSGK-NFSIRLANEILAVINGD------- 340 Rhizophagus irr...
NP_594222    164 VLKQAIAEISPLMKLVSAKR-FNKSVEFPMPLKERQRRRIALQWILGECKSSSPK-RLSDRIVKEIIAIRSKT------- 234 Schizosaccharom...
XP_002171791 161 VLHESVTKISPLMKLVTQKR-PTKNIQFPLPLNERQRRRFAIVWMLDASNSYKSK-SISERLAAEIIAVHNGT------- 231 Schizosaccharom...
EIF47558     159 ILKSALDTAAPLVITKTVKTgFAKNFIVPVPLTSRQRNRMAFLWILDSSDSRASN-DFSVRLAEEILNVXEGN------- 230 Dekkera bruxell...
P47150       152 ALEKSLDELAPLMMTKTFNTgVAKASVIPVPLNKRQRNRIAWNWIVQSANQRVSS-DFAVRLGEELTAIAKGT------- 223 baker's yeast
XP_002489741 151 LLRGCLDSLGPLCSTKTMKTgFAKNVTVPVPLSTRQRNRLAFKWILEGSDKRASK-DFSVRLAEEIISVIDGK------- 222 Pichia pastoris...
CCG82469     146 SLKEAIEKVSPLMKMIQRKQ-GSKNIPVPIPLSEKGRRRRAINWILEASQKRTGEkSFSARFAQELAAVLDGT------- 217 Taphrina deform...
EGF83811     101 VIDAAVQKASPFVKVVSFKR-RGKNVPTPFPLTDRQRNRTGILWIRDAALNGRSSqAAGVRIGKELLAILENK------- 172 Batrachochytriu...
EIE83132      81 ALREAIEVASPLLKISSTKK-GSKVVHVPTPLRERQRRRRAIVWMIEAASKRGEK-TFEERFAAEVFDVNEGT------- 151 Rhizopus oryzae...
Feature 1                           
CCM01191     204 rSAAFLKKEEVHKYAMMNR 222 Fibroporia radiculosa
ESA20603     341 -SAALKKKEQLHKLALANR 358 Rhizophagus irregularis DAOM 181602
NP_594222    235 -SNCFKKKDHLHRMCLVNR 252 Schizosaccharomyces pombe 972h-
XP_002171791 232 -SKCIKQKEQLHRLCLNNR 249 Schizosaccharomyces japonicus yFS275
EIF47558     231 -SRIMEKKALSHKLAIANR 248 Dekkera bruxellensis AWRI1499
P47150       224 -SSAFEKRDQIHKTAIAHR 241 baker's yeast
XP_002489741 223 -SSGFEKRSLMHKQAALHR 240 Pichia pastoris GS115
CCG82469     218 -SSAYQKKDAVHRLALANR 235 Taphrina deformans PYCC 5710
EGF83811     173 -GAVLQKREQVHKLALANR 190 Batrachochytrium dendrobatidis JAM81
EIE83132     152 -SSVLQKKLQVHKQALANR 169 Rhizopus oryzae RA 99-880

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