4I8O


Conserved Protein Domain Family
RNLA_N_1
?
cd14794: RNLA_N_1 
Click on image for an interactive view with Cn3D
N-terminal repeat domain of toxin RnlA; first out of two repeats
The Escherichia coli toxin RnlA functions as an mRNA endoribonuclease and is part of a two-component toxin-antitoxin system that promotes resistance to phage infections, together with the antitoxin RnlB. RNAse activity is located in the C-terminal domain. This N-terminal domain appears to participate in homodimerization and is the first out of two repeats.
Links
?
Statistics
?
PSSM-Id: 269817
Aligned: 12 rows
Threshold Bit Score: 97.3913
Created: 12-Nov-2013
Updated: 2-Oct-2020
Structure
?
Program:
Drawing:
Aligned Rows:
Download Cn3D
 
dimer interface
Conserved site includes 7 residues -Click on image for an interactive view with Cn3D
Feature 1:dimer interface [polypeptide binding site]
Evidence:
  • Structure:4I80: The N-terminal domain of Escherichia coli RnlA is involved in homodimerization, contacts at 4 A
Scroll to Sequence Alignment Display
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
Feature 1              ##                     #     ###                     #                    
4I8O_A         8 KNLNLVRANIETESRqfienknYSIQSIGPXpgsrAGLRVVFTRp----GVNLATVDIFYNGDGSTTIQYLTGANRSLGQ 83  Escherichia col...
WP_017103266   6 KNLNLERALIEELTKkmmeersYTLESFDDVpgtqTGKRVVFGHa----GKDFATVNIFFIKDGTSTIQYLTGANRELGK 81  Vibrio tasmanie...
WP_007647779   7 RNLNLNRSSIEQLSRdfieannFGLANISPMpgaqNGIRVVFTQa----GQQPATVDIYYNQDGTSSIRWQTGKNHPLSE 82  Shewanella sp. ...
YP_001501138   8 KNLNLVRANIEDVVNtfmdqhgFTLESIGDMpgaqNGKRVVYGQa----GSLYATVDIFFNNTGTSTVQFKTGRNQLLGK 83  Shewanella peal...
AGZ36374       7 KDINLNRSIIEDTTHrfvrengLKLRGYGEKpg-tPGLRLVVGCa----GIDDATLDIFFTNNGASTLQYKVGKNQELGQ 81  Pseudomonas sp....
YP_130024      4 NGLAMQTEKLSTYVDefl-tvhNAISMEARDit-qSKQTFKFIKt----GQDVATVIVYIKQGGLVTITYKTGKNHALGK 77  Photobacterium ...
WP_001286808   5 KNLNLDRDAIDAHVTkfl--ecNNMVQDGEPsvvgKAKRYKFGSt----GSKFAMVDLYLNQDGTTTINHKIGSNQELGE 78  Vibrio cholerae
WP_023327883   8 RDLNLNRENLDLNIQnfl--esHGYQLDGDIqtfpKRKRVVFGSt----GSEFSTVDFHLNHTGTTTIQWKLGKNQPVGE 81  Klebsiella pneu...
WP_005926183   2 KGLKLNREKLHNHIDte---lsKNYQVTKDIkp-nNLTIFKFIVt----GSPVAMLNIYENQDGTTTLNYKVGANQDLSK 73  Bacteroides sal...
WP_017691466   3 RNLNLNRDKIHCSIDkfl-rvkGLICTLAPFesfgGTRRRLYIS-----GECDTYIDFQFLSKGGTSIDLSSGKSNEFKE 76  Paenibacillus s...
WP_018054029  37 KKKNINRELIWRCLSdf---gaESLSKDQKT----STQYHLKGVy----DGNPFLFNIFENSDGTTTIGHATGQNRELFE 105 Methylobacter s...
YP_066883      1 MSFRDQNITIGQIEDh-----lQLLSKKGQTnkcvNKGRNVHCSfldenGYEKCLLIFYPKKFGITTIQFSCGKNKELSC 75  Desulfotalea ps...

Feature 1                       
4I8O_A        84 ELADHLFETINPAEF 98  Escherichia coli K-12
WP_017103266  82 ELADYLYESINPAEF 96  Vibrio tasmaniensis
WP_007647779  83 LLADHLFDTLNPSEF 97  Shewanella sp. HN-41
YP_001501138  84 RLADCLYETINPVEF 98  Shewanella pealeana ATCC 700345
AGZ36374      82 KLADALYETIHPDEF 96  Pseudomonas sp. VLB120
YP_130024     78 VFHDFLEQKCESADA 92  Photobacterium profundum SS9
WP_001286808  79 HFADYLKATINPAEF 93  Vibrio cholerae
WP_023327883  82 TLASYLRDTIDPAEF 96  Klebsiella pneumoniae
WP_005926183  74 KIAEQLVSICQIKEF 88  Bacteroides salyersiae
WP_017691466  77 ELANFIKEDPECSMG 91  Paenibacillus sp. PAMC 26794
WP_018054029 106 VLAEEIVRCCSFGEK 120 Methylobacter sp. UW 659-2-H10
YP_066883     76 EKAKQIINNFDVSSA 90  Desulfotalea psychrophila LSv54

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap