Conserved Protein Domain Family
GS_PAS-GGDEF-EAL
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cd14760: GS_PAS-GGDEF-EAL 
Globin sensor domain; coupled to PAS, DGC/GGDEF and EAL domains
In addition to the N-terminal sensing domain, globin-coupled-sensors in this bacterial subfamily have a signal-sensing PAS domain, and diguanylate cyclase (DGC/GGDEF) and EAL domains. The latter two domains are involved in the synthesis and degradation of c-di-GMP, respectively, and may be involved in regulating cell surface adhesiveness, and in the transition between planktonic and biofilm growth modes.
Links
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Statistics
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PSSM-Id: 271293
Aligned: 7 rows
Threshold Bit Score: 240.758
Created: 30-Nov-2012
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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heme bindinghomodimer
Feature 1:heme binding site [chemical binding site]
Evidence:
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                                  #  #         #  ##  #              
EES53865   22 LRTRRAFLEFTADDAARLSAIHPWLSSLRSRFIDDFYRHLASFEETRRFLPDEAAVeRLKKTQSDYFDSLTAgvYDTRYV 101 Leptospirillum fer...
ADL55023   22 IARRKEFLKFDETDVSLLTGLHARLQNVSRRFVEDFYAHMLKFEETRRFIPDAPSLeRLKRTQMSYFDSLTAgdYGSEYI 101 Gallionella ferrug...
BAM06312   23 HRLRRDFLGFTEEDGSRLKALHPHISSFYPQFIDSFYQHLIDFEKNRCFLQEEATVeFLKKNHTAYFNNLTTgiYDKDYI 102 Leptospirillum fer...
EIC27946   12 VTTRKAFLGFSEADVHHLKKLHEAFEDRGPTFAKRFCEHMLSFPETRRFITDSSILdRLQQAQAEYFGTLTAghYGSDYI 91  Methylomicrobium a...
EKU82859   22 IAARRSFLQFDERDAAVLREVHALLDQERDTFSDSFYAHLLAFPRLRELLADSETTsRLRRAQAGYFSSLTAgdYGPAYI 101 Massilia timonae
EPZ17333   22 ILRRKAFLEFDEADAVRLRQIHATLQKHSDDFAQALCAHLTAFEETRCLVGGADILkRMQDSQSKYFREISEarYDHDYF 101 Thauera terpenica ...
GAD20762    7 FQHRKEFLNLTAKDERILQGLHAALGEGAPGFVEGFYRHLLSFEEMRALIPDDDSLaRLQRLQTRYFHTLTAgrYDEAYG 86  Acidovorax sp. MR-S7

Feature 1          #  ##    #   #   ##                                       #    
EES53865  102 HDRLKIGAVHQAIGLSPQWYLGAYVKYLSGLLPEIRNFLadrpdEFLAAWQSLVKVAMFDMSLALDAY 169 Leptospirillum ferrodiazotrophum
ADL55023  102 LHRLRVGVVHQHIGLEPKWYLGAYSKYLAGLLPELWQQLgkepeAFVATCQSLIKIVMLDMGLALDTY 169 Gallionella ferruginea ES-2
BAM06312  103 SSRLKIALIHHSIGLSLQWYLGVYVRYLSDFLPKIRLLTsdlseEFTSVVVSFLKVMMFDLGFALDTQ 170 Leptospirillum ferrooxidans C2-3
EIC27946   92 RNRLRAGIAHQRIGLETQWYLGAYAKYLVDLMPEIWQKLgadheAFIAALQSLLKVVLLDMGLAVDTY 159 Methylomicrobium album BG8
EKU82859  102 HERLRVGATHQRIGLDPKWYIGAYRKYLSELSSLLWQKLdhdpaRFIEAWDAVLKVVCFDIGLALDTY 169 Massilia timonae
EPZ17333  102 RRRQQVGFHHQHIGLSPEWYLGIYGKYLSVLLPRIRDHFgadidGFCATMLAFFKAILLDMSLTIGAY 169 Thauera terpenica 58Eu
GAD20762   87 LERQRVGLTHARVGLPPGWYLGAYSQYLTQLLPVVARLGlp-adDWVAALQALVKVVFLDMGLAIDTY 153 Acidovorax sp. MR-S7

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