1PYI


Conserved Protein Domain Family
ZIP_Ppr1
?
cd14723: ZIP_Ppr1 
Click on image for an interactive view with Cn3D
Leucine zipper Dimerization coil of Ppr1-like transcription factors
Ppr1/Ppr1p activates transcription of the URA1, URA3, and URA4 genes, which encode enzymes involved in the regulation of pyrimidine levels. Also included in this subfamily is Colletotrichum acutatum Nir1 which plays a role during nitrogen-starvation conditions. Proteins in this subfamily are members of the Gal4p family of transcriptional activators which contain an N-terminal DNA-binding domain with a Zn2Cys6 binuclear cluster that interact with CCG triplets and a leucine zipper-like heptad repeat that dimerizes. Dimerization allows binding of targets which contain two CCG motifs oriented in an inverted (CGG-CCG), direct (CCG-CCG), or everted (CCG-CGG) manner.
Links
?
Statistics
?
PSSM-Id: 271240
Aligned: 30 rows
Threshold Bit Score: 35.8185
Created: 13-Sep-2013
Updated: 2-Oct-2020
Structure
?
Program:
Drawing:
Aligned Rows:
Download Cn3D
 
dimer interfacecoiled coil
Conserved site includes 14 residues -Click on image for an interactive view with Cn3D
Feature 1:dimer interface [polypeptide binding site]
Evidence:
Scroll to Sequence Alignment Display
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
Feature 1     #   ##  ## ## ### ##  # #
1PYI_A     45 VPRSYVFFLEDRLAVMMRVLKEYGV 69   baker's yeast
ABB13598   66 APKSYVALLQARIELLEKVLWLHSI 90   Glomerella acutata
EEA25115   59 RPRAYVQALITRLEQLRAVKARVSS 83   Penicillium marneffei ATCC 18224
EEU34256   78 APKAYVRQLQARIQILEEILRMHSI 102  Nectria haematococca mpVI 77-13-4
EEU34905   66 APKSYVDLLRSRIDHLERLLQAHSI 90   Nectria haematococca mpVI 77-13-4
EKD05589   78 TPKAYVASLESRVRSLESILKSHGI 102  Trichosporon asahii var. asahii CBS 8904
EOD48680   44 VPRSYLHALNVKVEELEAEIRSLKA 68   Neofusicoccum parvum UCRNP2
ESX01416   64 VPRSYVVSLESRVEELENRLRSLEG 88   Ogataea parapolymorpha DL-1
EGX47440   90 IPRSYVSHLEERVAFLEKQLASGAQ 114  Arthrobotrys oligospora ATCC 24927
EMD69613   78 IPRNYVVHLQQKVRQLEKQLADLER 102  Cochliobolus sativus ND90Pr

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap