4BHU


Conserved Protein Domain Family
BslA_like
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cd14670: BslA_like 
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Bacterial immunoglobulin-like hydrophobin BslA and similar proteins
BslA (YuaB) is a protein from Bacillus subtilis acting as a hydrophobin, which forms surface layers around biofilms and participates in biofilm assembly. BslA contains an unusually hydrophobic "cap structure", which is essential for its activity and for the ability of bacteria to form hydrophobic, non-wetting biofilms. A number of domains in various proteins from Bacilli and other bacterial lineages appear related to BslA, but do not conserve the hydrophobic cap.
Links
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Statistics
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PSSM-Id: 270614
Aligned: 23 rows
Threshold Bit Score: 63.1277
Created: 2-Mar-2014
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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hydrophobic cap
Conserved site includes 8 residues -Click on image for an interactive view with Cn3D
Feature 1: hydrophobic cap, 8 residue positions
Conserved feature residue pattern:[LIMV] [LIMV] [LIMV] [LIMV] [LIMV] [LIMV] [LIMV] [LIMV]Click to see conserved feature residue pattern help
Evidence:
  • Structure:4BHU: In the crystal, Bacillus subtilis BslA forms aggregates that bury the hydrophobic cap, contacts at 4 A
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                         ## #                                            
4BHU_A          5 SASLFATITGASXT---EWSFSDIELTYRPNTLLSLGVXEFTLPsGFTANt-kDTXNg-----NALRTTQILNnGKTVRV 75   Bacillus subt...
WP_020493018  319 ANTNDGKLSVSPASt-iAGATKNIYLVYLPGEDMNNGTVEFFLPdRYLAIagqDKITing-tmNALTSEQISDaGQRVKI 396  Dehalobacter ...
NP_391660      28 AHAQSASIEAKTVNstkEWTISDIEVTYKPNAVLSLGAVEFQFPdGFHATt-rDSVNg-----RTLKETQILNdGKTVRL 101  Bacillus subt...
WP_007063106  442 ATTTAGAITLSPANg-nRGASQNIEVIYTPGETMTNGTVLFTLPeGFSADlttDKFKiadgeeTALNQEEIGNnGQTVTL 520  Clostridium c...
YP_002504642  599 NVTLPGRLEISPVTg-eAATVKDFEITYTSKDDFSNGTVTFWLPdGFPAFe-tDTVKigngteVTLNPSQRLN-VRTLSF 675  Clostridium c...
YP_004266634  333 EETPDGMLEITPTSs-vNGNTQTVTLTYTLASAMDNGTLEYVLPaQITAApelDKIKigsggeDSLMAKQVLDeGRKLSI 411  Syntrophobotu...
WP_006718076  613 TGNVGTKAGGFGVNg-hGGVVGETVLTYTLGEDYNKGQIEFLLPnGIVAMe-gDLVRianaegMGISSDTISDnGHKVTL 690  Desulfitobact...
WP_008360418   43 PAALYAKITGASKQ---EWSFSDIELTYRPNSVLSIGAVEFTLPaGFQATt-kDIINg-----KALKDSYILNnGKTVRI 113  Bacillus sp. ...
WP_003186319   71 NPTQKPVLEAKTINsnkEWSTSDIEITYRPNAFVGSSYVEFHFPyRFHASt-rDTLNg-----KTLDYTQILNdGQTVRV 144  Bacillus lich...
WP_010790060   10 PLAPSLTITAVQNDa--EGTTTDLILTYSPNSVLSLGGVVFRLPeGFTATt-nDTINn-----SALSASQISEgGRKVTL 81   Bacillus atro...

Feature 1          # #  #                            # #             
4BHU_A         76 PLALdlLGAGEFXLKLNNKtlPAAGTYTFRAENksLSIG--NXFYAEASID 124  Bacillus subtilis subsp. subtilis str. NCI...
WP_020493018  397 SGLNv-TTGQKIILTLNDKsvQDVGNYTFKVVAdaDGSG--ILRPSSGSLT 444  Dehalobacter sp. FTH1
NP_391660     102 PLTLdlLGASEFDLVMVRKtlPRAGTYTIKGDVv-NGLGi-GSFYAETQLV 150  Bacillus subtilis subsp. subtilis str. 168
WP_007063106  521 TDVNa-STSSAIVLKLINKtiPDANTYNFKVAAdsDGLGtaKTWSAGTETE 570  Clostridium carboxidivorans
YP_002504642  676 TNLNl-SKGQKIIVKLRNKtvPQGGEYVFSAVTdaDGTG--PKVPTSGQDE 723  Clostridium cellulolyticum H10
YP_004266634  412 SGITa-AAGEKIVLTLANKtvPGVGNYAFRIFAdaDGEG--DILPSSGTGK 459  Syntrophobotulus glycolicus DSM 8271
WP_006718076  691 TGVSa-KKDDTVVLTLSRD--IEIGRWDFKVIGdsDGNGp-ILQVQEPSIT 737  Desulfitobacterium metallireducens
WP_008360418  114 PARIdlFGSAQYTLQLSHKvlPAAGTYTFRAENraISIG--STFYAEDTID 162  Bacillus sp. HYC-10
WP_003186319  145 PVYA--LSSSEFKLVMVRKtlPNAGTHRITAEL--QQNGk-NINHAETTLE 190  Bacillus licheniformis
WP_010790060   82 PLTLnlLGIAQFTLQLKNKtlPAEGIYSFSAENtvLIIG--SLLPATTELY 130  Bacillus atrophaeus

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