2HAK


Conserved Protein Domain Family
UBA_MARK1
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cd14405: UBA_MARK1 
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UBA domain found in serine/threonine-protein kinase MARK1 and similar proteins
MARK1, also called MAP/microtubule affinity-regulating kinase 1 or PAR1 homolog c (Par-1c), is a kinase-regulating microtubule-dependent transport in axons and dendrites. It is involved in the specification of neuronal polarity, in axon-dendrite specification, and in the synaptic plasticity in adult neurons. It has been implicated in Alzheimer's disease, cancer, and autism.
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Statistics
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PSSM-Id: 270588
Aligned: 4 rows
Threshold Bit Score: 86.8823
Created: 23-Jul-2012
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2HAK_A       288 NDTKRIDIMVTMGFaRDEINDALINQKYDEVMATYILLGRK 328 human
XP_419403    331 NDTKRIDIMVTMGFsREEIHESLVNQKYDEVMATYLLLGRK 371 chicken
NP_001085126 331 NDTKRIDIMVTMGFsREEINNAVVNQKYDEIMATYLLLGRK 371 African clawed frog
NP_001107948 331 SDTKRIELMITMGFpKDEITEALVGQKYDEVMATYLLLGRK 371 zebrafish
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