CUE2 domain found in yeast ubiquitin-binding protein CUE2 (Cue2p) and similar proteins
Cue2p, also called coupling of ubiquitin conjugation to ER degradation protein 2, is encoded by the open reading frame (ORF) YKL090W. It is involved in the intramolecular monoubiquitination that serves as a regulatory signal in a variety of cellular processes in yeast. Cue2p contains two tandem CUE domains at the N-terminus. Both of them can bind monoubiquitin independently. This model corresponds to the second CUE domain.
Jiyao W et al.(2023). "The conserved domain database in 2023.",