2VN6,4IU2,2B59,4DH2,1OHZ


Conserved Protein Domain Family
Dockerin

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cd14253: Dockerin 
Click on image for an interactive view with Cn3D
Dockerin repeat domain
Dockerins are modules in the cellulosome complex that often anchor catalytic subunits by binding to cohesin domains of scaffolding proteins. Three types of dockerins and their corresponding cohesin have been described in the literature. This alignment models two consecutive dockerin repeats, the functional unit.
Statistics
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PSSM-Id: 271212
Aligned: 8 rows
Threshold Bit Score: 43.5649
Created: 3-May-2013
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
Conserved site includes 9 residues -Click on image for an interactive view with Cn3D
Feature 1: Ca binding site [ion binding site], 9 residue positions
Conserved feature residue pattern:D x x x [DE] [DENS] x x [DE]Click to see conserved feature residue pattern help
Evidence:
  • Comment:Two dockerin repeats bind two calcium ions
  • Structure:1OHZ: dockerin repeats from Clostridium thermocellum Endo-1,4-beta-xylanase Y bind calcium ions, contacts at 4 A

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1          # # # #    #                                             # # #                 
2VN6_B          5 GDYNNDGNVDSTDFAGLKKYIMaa--------------------------dhAYVKNLDVNLDNe-------------VN 45   Clostridium c...
4IU2_B        123 GDTDLNNIVDGRDATATLTYYAatstdgkdattvalspstlvggnpesvyddFSAFLSDVKVDAgkeltrfakkaerlID 202  Ruminococcus ...
2B59_B        101 GDIVKDNSINLLDVAEVIRCFNatk------------------------gsaNYVEELDINRNGa-------------IN 143  Clostridium t...
4DH2_B          8 GDVNADGVVNISDYVLMKRYILriiad---------------------fpadDDMWVGDVNGDNv-------------IN 53   Clostridium t...
1OHZ_B          2 GDVNGDGTINSTDLTMLKRSVLrait-----------------------ltdDAKARADVDKNGs-------------IN 45   Clostridium t...
YP_003958384  276 GDVNADMKVDILDAQLIALSCAagge-----------------------meaSRKARGDVNGDAq-------------VN 319  Eubacterium l...
YP_004044329  352 GNVNRDDTVDATDASAVSADVAk----------------------------gQSPEYADVNDDGr-------------VS 390  Halogeometric...
YP_003958382 2231 GSFTGDDTIDIIDAQKIALFLTaget-----------------------pseRQKAAGDVNFDGk-------------VD 2274 Eubacterium l...
Feature 1           #         
2VN6_B         46 AFDLAILKKYLL 57   Clostridium cellulolyticum
4IU2_B        203 GRDASSILTFYT 214  Ruminococcus flavefaciens
2B59_B        144 MQDIMIVHKHFG 155  Clostridium thermocellum
4DH2_B         54 DIDCNYLKRYLL 65   Clostridium thermocellum ATCC 27405
1OHZ_B         46 STDVLLLSRYLL 57   Clostridium thermocellum
YP_003958384  320 IIDAQQIAQNAV 331  Eubacterium limosum KIST612
YP_004044329  391 AIDAMFIAQYAA 402  Halogeometricum borinquense DSM 11551
YP_003958382 2275 IIDAQQIALYLA 2286 Eubacterium limosum KIST612

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