3W1O


Conserved Protein Domain Family
DMP12
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cd14245: DMP12 
Click on image for an interactive view with Cn3D
Putative DNA mimic protein DMP12
The Neisseria sp. protein DMP12 has been shown to interact with the bacterial histone-like protein HU and may do so by acting as a DNA mimic. It is likely to play a regulatory role, but not via direct competition for binding of HU, which is involved in maintenance of the bacterial nucleoid structure.
Links
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Statistics
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PSSM-Id: 271204
Aligned: 3 rows
Threshold Bit Score: 180.932
Created: 2-Mar-2014
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
Download Cn3D
 
putative HU
Conserved site includes 10 residues -Click on image for an interactive view with Cn3D
Feature 1:putative HU binding interface [polypeptide binding site]
Evidence:
  • Comment:negatively charged residue sidechains may mimic DNA
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1               #     #  #  #                                #                # #      #
3W1O_A        6 NLLIFCLKDNvsisEYTEMIDWAYKNIqseTVVEITENQIIEYQNrGLWRLVSEITDNWLFgPSEGDWLIDkESILAVKE 85  Neisseria mening...
ZP_11624357   6 LYPVFCLERNieinDLPKMIDWAYANAgsqTVVILNEEEVRYYEStGLWGIISEETDNWLFgLHEDDWIFDfDIMQNIIN 85  Moraxella catarr...
ZP_16001731   5 NLLIFCLKDNvsisEYTEMIDWAYKNIqseTVVEITENQIIEYQNrGLWRLVSEITDNWLFgPSEGDWLIDkESILAVKE 84  Neisseria mening...

Feature 1            #                    #       
3W1O_A       86 KLQNSDfstEPLVKNIIHVLEYAIKNEKTVIFHF 119 Neisseria meningitidis MC58
ZP_11624357  86 AINSKYikiDQTVGKILFILDYAIANQKSVVFYL 119 Moraxella catarrhalis 7169
ZP_16001731  85 KLQNSDfstEPLVKNIIHVLEYAIKNKKNSNFSF 118 Neisseria meningitidis 98008

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