Many characterized members of the UbiA prenyltransferase family are aromatic prenyltransferases and play an important role in the biosynthesis of heme, chlorophyll, vitamin E, and vitamin K. They contain two copies of a motif similar to the active site DxxD motif of trans-prenyltransferases and are potentially related. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.
Feature 1: putative active site [active site], 4 residue positions
Conserved feature residue pattern:d d d d
Evidence:
Comment:based on homology modeling using structures of trans prenyltransferases that are helical enzymes containing two D-rich motifs in the active site
Jiyao W et al.(2023). "The conserved domain database in 2023.",