3VPB


Conserved Protein Domain Family
LysW
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cd13946: LysW 
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Lysine biosynthesis protein LysW
LysW functions as a carrier protein in the biosynthesis pathway of lysine. The C-terminal glutamate sidechain of LysW attaches to the amino group of alpha-aminoadipate (AAA); this peptide bond formation is catalyzed by the ligase LysX. AAA remains associated with LysW throughout its biosynthetic conversion to lysine. LysW also acts to protect the amino group of glutamate in arginine biosynthesis.
Links
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Statistics
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PSSM-Id: 260118
Aligned: 29 rows
Threshold Bit Score: 58.8181
Created: 20-Aug-2013
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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Conserved site includes 4 residues -Click on image for an interactive view with Cn3D
Feature 1: Zn binding site [ion binding site], 4 residue positions
Conserved feature residue pattern:C C [HC] CClick to see conserved feature residue pattern help
Evidence:
  • Structure:3VPB: Sulfolobus tokodaii LysW binds Zinc ion, contacts at 4 A
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1         #  #                 #  #                            
3VPB_E        4 LKCPVCNGDVNVPDDaLPGEIVEH-ECGAQLEVYNDh-GRLALRLAEQVGEDWGE 56  Sulfolobus tokodaii str. 7
YP_001435985  3 AKCPVCGAEIELPDDvMDGEIVECpQCGATLEVKKSg-DKVELKVAEEVGEDWGQ 56  Ignicoccus hospitalis KIN4/I
ABZ07071      1 MKCPECDADLNIPEDaAVGEIVSCsDCGADYEISKKdgSTVEIKEAETVGEDWGE 55  uncultured marine crenarchaeote HF4000_AN...
YP_001582628  2 SKCEECDADISIPSDaLEGEIVTCpECGASFELAKGs-DGFDLKPAQTVGEDWGQ 55  Nitrosopumilus maritimus SCM1
YP_006862050  3 VKCPECDAEIKIPSDsIEGEIVTCpDCGASYELVKSg-EGFEIKPAQVVGEDWGQ 56  Candidatus Nitrososphaera gargensis Ga9.2
YP_024251    26 GKCKMCGESIEMPDDaIVGELVECgGCGMTYEISAIsnGNVSLKSAEHVGEDWGE 80  Picrophilus torridus DSM 9790
YP_875072     2 ATCSECDGSIHVPADsLEGEIVTCpECGAGFELVKTq-EGFELKPAQTVGEDWGQ 55  Cenarchaeum symbiosum A
YP_006863573  5 VECQECGADISVPEDaVVGEIVTCpDCGGDYEIASKsgDKVELKPAETVGEDWGQ 59  Candidatus Nitrososphaera gargensis Ga9.2
NP_560328     8 VQCKVCGTEFELPEDvMDGEIASCpTCGARYIVRLKg-GSVTLEEFKGDVEDYGE 61  Pyrobaculum aerophilum str. IM2
YP_876381     1 MKCEECDAVLNPPKDaISGEIISCpDCGSDYEIVKKegGEIELKKAEKVAEDWGE 55  Cenarchaeum symbiosum A

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