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Aromatic Prenyltransferases (PTases) associated with tryptophanase This group of bacterial and fungal proteins shows homology to the DMATS/CymD family of ABBA prenyltransferases, which prenylates indole, tyrosine, and xanthone derivatives. Some of the members, mostly fungal proteins, are associated with tryptophanase-like domains (Tnase) which catalyzes the degradation of L-tryptophan to yield indole, pyruvate and ammonia, or the degradation of L-tyrosine to yield phenol, pyruvate and ammonia. This suggest that these otherwise uncharacterized proteins may exhibit multiple functions. |
Jiyao W et al.(2023). "The conserved domain database in 2023.",