1GWL,2YPJ,1WCU,4AFM,1W8T


Conserved Protein Domain Family
CBM29_CBM65
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cd13748: CBM29_CBM65 
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family 29 and family 65 carbohydrate binding modules
Members of this family bind to polysaccharides that are components of plant cell walls. CBM29 is present in cell-wall degrading multi-enzyme complexes from the anaerobic fungus Piromyces equi, CBM65 can be found in endoglucanases expressed by Eubacterium cellulosolvens and has a preference for xyloglucans.
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Statistics
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PSSM-Id: 259840
Aligned: 7 rows
Threshold Bit Score: 111.519
Created: 5-Apr-2013
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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carbohydrate
Conserved site includes 7 residues -Click on image for an interactive view with Cn3D
Feature 1:carbohydrate binding site [chemical binding site]
Evidence:
  • Structure:2YPI: CBM65B from Eubacterium cellulosolvens binds a xyloglucan, contacts at 4 A
  • Structure:1GWL: CBM29 from Piromyces equi binds mannohexaose, contacts at 4A
  • Structure:1W8T: A CBM29 mutant from Piromyces equi binds cellulohexaose, contacts at 4 A
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                      #                                     # #      # #                
1GWL_A        35 GAMIINPQeg---kYGAV-SLKRNSgsf-----rgGSLRFDMKNeGKVKILVENSe----aDEKFEVETispsdeyVTYI 101  Piromyces equi
2YPJ_A        35 GSNHADFKawggddWPSAfEISPKYepmkldlnknFEIKVDYNG-ADIVLIFARWd----kDIWAQISPyyv--vdGTAV 107  Eubacterium ce...
1WCU_A        34 NSLVLTADpd---eYGAI-SLKNLNsnyy---gkgGCIYLQVKTeTEGLVKVQGVrgy-deTEAFNVGSfrsssdfTEYK 105  Piromyces equi
4AFM_A        10 GSKHVEFTdwggtdWPSAyELQPPYqtxpfdlnknFEIKVDYSG-ADIVLIFARWehgskpQIWAQISPyyv--vdGTAV 86   Eubacterium ce...
1W8T_A        35 GAMIINPQeg---kYGAV-SLKRNSgsf-----rgGSLRFDMKNeGKVAILVENSe----aDEKFEVETispsdeyVTYI 101  Piromyces equi
AAK20910     368 GAMIINPQeg---kYGAV-SLKRNSgsf-----rgGSLRFDMKNeGKVKILVENSe----aDEKFEVETispsdeyVTYI 434  Piromyces equi
ZP_10167476   46 GSKHVEFTdwggtdWPSAyELQPPYqtmpfdlnknFEIKVDYSG-ADIVLIFARWehgskpQIWAQISPyyv--vdGTAV 122  Eubacterium ce...

Feature 1                           #   #                   
1GWL_A       102 LDVDfdl---------pfDRIDFQDAPGnGDRIWIKNLVHSTG 135  Piromyces equi
2YPJ_A       108 FTKEqiakaygsddfsglDYIAVKPLPS-EEGVTVTKVSGIYT 149  Eubacterium cellulosolvens
1WCU_A       106 FEVDdey---------qfDRIIVQDGPAsNIPIYMRYIIYSTG 139  Piromyces equi
4AFM_A        87 FTKEqiakaygsddfsdlDYIGVKPLPS-ADGXTVTKIVASYT 128  Eubacterium cellulosolvens
1W8T_A       102 LDVDfdl---------pfDRIDFQDAPGnGDRIWIKNLVHSTG 135  Piromyces equi
AAK20910     435 LDVDfdl---------pfDRIDFQDAPGnGDRIWIKNLVHSTG 468  Piromyces equi
ZP_10167476  123 FTKEqiakaygsddfsdlDYIGVKPLPS-ADGMTVTKIVASYT 164  Eubacterium cellulosolvens 6

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