4HN3,3N2Q,2QX2,3IB5


Conserved Protein Domain Family
CamS_repeat_1
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cd13441: CamS_repeat_1 
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N-terminal repeat domain of CamS sex pheromone cAM373 precursor
This family includes CamS, from which Staphylococcus aureus sex pheromone staph-cAM373 is processed. The protein contains two structurally similar repeats in a tandem arrangement. The heptapeptide cAM373 is a Streptococcus faecalis pheromone, secreted by recipient cells, which induces a mating response in donor cells that contain particular conjugative plasmids. cAM373 is also excreted by Staphylococcus aureus. The family also contains sex hormone precursors from other bacteria.
Links
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Statistics
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PSSM-Id: 240444
Aligned: 76 rows
Threshold Bit Score: 143.127
Created: 19-Dec-2012
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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putative dimer
Conserved site includes 14 residues -Click on image for an interactive view with Cn3D
Feature 1:putative dimer interface [polypeptide binding site]
Evidence:
  • Structure:4HN3: Lmo1757 from Listeria monocytogenes forms homodimer, contacts at 4 A
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1       # ###     ## ##            #  ##  #                 # #                         
4HN3_A       32 TVLPYKASKSRGLVVSni-------ysRYDINELESGLXRVSQNKYspdnYLFQEGQYLDKETLEKWLDRKSdknpngln 104 Listeria monocyt...
ZP_07831584  49 SALLPFSVSDAGQKHAqmq------tnLSDTLTIGTGLMELSKEYFssktYAFRGGKYLDYNTLDASADNSGllgrtskk 122 Clostridium sp. ...
CBK88054     39 AMLPFESSDTRVKHVGli-------sdQDIRIEIESGLMDLSKQYFdpssVGYRTHTFLDFDELDATDGSRGllgtlrdd 111 Eubacterium cyli...
ZP_03636776  49 PHELSEGRYWRGNTNS-----------RFDLMQMPKELIELSKQHFsvkdNYLQAGQILEYEDIQELQRYESsdhsygln 117 Holdemania filif...
ZP_07672053  50 ALLPFSASDAGQKHAQmq-------tnLSDTLTIGTGLMELSKEYFssktYAFRGGKYLDYNTLDASADQSGllgrtskk 122 Erysipelotrichac...
ZP_06645384  46 ALLPFEASSSRIKHAYtt--------nLNEAMIIGVGMMNLSKEHFspddYAYKESQFLSYDALDATGLDRVgllgrtse 117 Erysipelotrichac...
ZP_02076650  45 ALLPYQSSDASIKHATln-------tnMIDTLQIGTGLMELSKEYFssdtHTFREGEFLDFDTLDAATDQSSgllgrfnk 117 Eubacterium doli...
ZP_08011605  39 DDSYYKIIKTESGDSElregfyldygaTSDFKTIGRGLQILSSDYFstsnHYMSEGQYLKLSLKNELVKRKSdyslqpas 118 Coprobacillus sp...
ZP_08083206  46 ILTPFKTSPLRQNYGTnf--------rEVDMIEIGRRLQDKSKDHFnpanFNISEGSIINDDHYDQLLRHESknypygln 117 Erysipelothrix r...
ZP_02428668  44 RVVNFNTNLSREDYYTaf-------gnTMDFQTIGRELQILSTDHFstndYYMSEGQYLKTDDMNQLLKRSEdtskypyt 116 Clostridium ramo...

Feature 1                                                                                       
4HN3_A      105 pas-----------------ngngenrkpiYLAHILEQDYLkqtdkdtvaLGGISIALAXNSvdyyqkekygdtyeqpIS 167 Listeria monocyt...
ZP_07831584 123 nanglnpavg---dvfptddgdkkitandvLLLDIFEYDWYqn-----keLKGLSLALVFNDkigte------pkeatID 188 Clostridium sp. ...
CBK88054    112 npnglnps------rdeafdtgngevtgatILVDIYELDWYntn----dnLRGISLALVVNDevedda-----gntyeIT 176 Eubacterium cyli...
ZP_03636776 118 psgnf-------------eisdaiilerpyIVYGIVEIDFIsked--qktLNGISVGILMNSsvtsg------dstvqIP 176 Holdemania filif...
ZP_07672053 123 nanglnpavg---dvfptddgdkkitandiLLLDIFEYDWYqn-----keLKGLSLALVLNDkigte------pdeatIN 188 Erysipelotrichac...
ZP_06645384 118 knpngmnpai--gteidtnngkkkigsqdvLLIDIYELDWYdg-----kdLEGLSLGIVLNDeigds------vnpdiVS 184 Erysipelotrichac...
ZP_02076650 118 ktnsiglnpaikdefpvegggtvkigasdiLLLDIQEFDWYkn-----geLAGLSLAFVLNDevgee------nntqrIR 186 Eubacterium doli...
ZP_08011605 119 gt-------------------tiggikdpiMLQNVQEQDYFvkdg-kgytLKGISFSLIIEPrnsdns-----vlaepMS 173 Coprobacillus sp...
ZP_08083206 118 pvdgt------------efvekgrkiqtptFVRDVVEVNFHsgnd--inkIDGVGIALVMKRvqteagt---glpvrlSD 180 Erysipelothrix r...
ZP_02428668 117 lqaq--------------rgttiggvanpiMVSTVHEQDYYekng-seyvLKGLSLAIVLDPrdekne-----rldtsLD 176 Clostridium ramo...

Feature 1                                                                                     
4HN3_A      168 DSELLAQGKEXSATVLNRIRQtkg---lenVPVTIAIYKQGARda-vAPGNYIAYATANg-----------dSLSNWK 230 Listeria monocytog...
ZP_07831584 189 SDKMKLYGEECARKLVNYLRKakpe-ignnTPIYVALYNTSSDda-tLPGTYFEEAYFEsktn-----aefkAINEKW 259 Clostridium sp. HGF2
CBK88054    177 KEKLQNYIEVTAGKLVNYMRErfnd-isarIPIYIAAYSLDSSqe-sLGGYFYEGMFEG-------------SSGSYN 239 Eubacterium cylind...
ZP_03636776 177 QDKLYTYASTIGRKLERYFRNkaev--dadLPIYITFYSSNSTss-sVPGAFIGQGLFTs------------RSGQFT 239 Holdemania filifor...
ZP_07672053 189 SDKMKLYGEESARKLVNYLRKakpe-igsnTPIYVALYNTSSEda-tLPGTFFEGAYFEs-----------kTNAEFK 253 Erysipelotrichacea...
ZP_06645384 185 DAKLRAYGEEVGRKVVSYLRKthpe-igqkTPIYVTLFKESGVnt-tLPGTFIEEAYFEs-----------kTIGEYS 249 Erysipelotrichacea...
ZP_02076650 187 EDKMDVYAKETVRKAVNYIRKkipg-vgndLPIFVALYDINSVde-aLPGTFYQAAFFEtkid-----gdfyDIKENW 257 Eubacterium dolich...
ZP_08011605 174 NSDIESYGRECIQKFYNVIRQadefkkvkdLPILITVYKATNTatssVDGNYILKSYCQkdv-------geiNKVNHE 244 Coprobacillus sp. ...
ZP_08083206 181 ETLYEIARTSIGNRLISYLRTieg---msdVPIYLVLYAQESDtd-tLPGKYLPGRVIGegffesrggqfeqTSEKWT 254 Erysipelothrix rhu...
ZP_02428668 177 ESLVVDFGREAISKLYKYLQSkkd---lkdIPANICVYYATNTnesdINGRYILKSYCDg------------SVGNIE 239 Clostridium ramosu...

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