4HN3,3N2Q,2QX2,3IB5


Conserved Protein Domain Family
CamS_repeat_2
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cd13440: CamS_repeat_2 
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C-terminal repeat domain of CamS sex pheromone cAM373 precursor
This family includes CamS, from which Staphylococcus aureus sex pheromone staph-cAM373 is processed. The protein contains two structurally similar repeats in a tandem arrangement. The heptapeptide cAM373 is a Streptococcus faecalis pheromone, secreted by recipient cells, which induces a mating response in donor cells that contain particular conjugative plasmids. cAM373 is also excreted by Staphylococcus aureus. The family also contains sex hormone precursors from other bacteria.
Links
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Statistics
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PSSM-Id: 240443
Aligned: 74 rows
Threshold Bit Score: 96.8376
Created: 19-Dec-2012
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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putative dimer
Conserved site includes 27 residues -Click on image for an interactive view with Cn3D
Feature 1:putative dimer interface [polypeptide binding site]
Evidence:
  • Structure:4HN3: Lmo1757 from Listeria monocytogenes forms homodimer, contacts at 4 A
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                          ## ##     #         # #      ###### ## ### ## 
4HN3_A       234 EKNYVLPste---sakDHKTDNDNFLNFKKAIEDYYPNFTGVVGRGRYEDGQLAELNIDIPLQFYGEAEIIGFTQYVTDL 310 Listeria monocy...
YP_004322075 265 RQYVVYGvd-----qaPREEDNTSFSRFRGEIESFFPELSGIVGVGQYDNGKLNGIDFHINTPFDGYTENIALVQHVIAS 339 Aerococcus urin...
ZP_03636776  243 EQWVLIPsdq---ataLDGVLSSQFSTVKAGVKDFMPENVNIIGKARYTNDTADYLKITVTVQAKSYTEIYSLMQLLNEL 319 Holdemania fili...
ZP_06645384  253 EAWALFPssa---atkLDSTNATYFDRLVKEIKNFFPEDTAVIGTGHFKDKELASLTIDISMHAKTWPEANAMMQKVNSS 329 Erysipelotricha...
ZP_03487840  240 QEWVLVPssr---fteLDATAADEFTTFKEEIANVLPDNTFVTGEAKFESKKLRKLNLTITAHGKTAGEVLAIIEHAKDQ 316 Eubacterium bif...
YP_002770169 239 EEYFLFPsse---veqKYPEQSLQYDKLMRQSKGYFPEYIGMTGLGRFMDGKLTEITITATAEYDSRTEALQFTQFAAGS 315 Brevibacillus b...
ZP_02867892  243 YHNYMFSsee---atlADEEVASQFEIFKSNMKKASTEAVGVIGYGRYKDNTIQSMNINLNVNVKTYEELIYLVSTAADE 319 Clostridium spi...
ZP_05648907  251 EAHIILPvaagvtnaaTDDGLDNKFKTFRDAVISFFPDLSGVTGNAYYVDDQLQKLVLKVESNYYSKTEITSFVQYSAKQ 330 Enterococcus ga...
ZP_06807288  278 QDFVVYGvd-----daPNEEDTVAFTRFRDQIQSFYPQLSGLSGVGYYQDNEQQNINIVIYSQFDGYSEIIALSQQAIST 352 Aerococcus viri...
ZP_07672053  257 EKWALFPtst---atkLDGTNATYFDRYKASFQDFLGQDIDMIGKGHFMDNELEALRINVKLHAKSADEVIAAVQLLDER 333 Erysipelotricha...

Feature 1                    # #         # #         ###
4HN3_A       311 VGQHIPKt-ADLQVNISTsDGPAALITRKAneDAATAHI 348 Listeria monocytogenes EGD-e
YP_004322075 340 LDAIYPKd-VQMQVTVEGpSRMTANITRLSgqSQFQYTV 377 Aerococcus urinae ACS-120-V-Col10a
ZP_03636776  320 SANFSSTd-MELIIEIKQlEETVMILHREKgtMKTTVLD 357 Holdemania filiformis DSM 12042
ZP_06645384  330 LSIFSSTs-FAIKVRLKSdDVLIGAMQREKgsSKVTVIQ 367 Erysipelotrichaceae bacterium 5_2_54FAA
ZP_03487840  317 MSTFETKk-CDYLITILNdDTVYALIERKSgsSECNVIS 354 Eubacterium biforme DSM 3989
YP_002770169 316 INQLFDKs-VHVNLYVQSmNKPLSIYIRPTs-GEPYMHI 352 Brevibacillus brevis NBRC 100599
ZP_02867892  320 VDSQFTG--FDVKVLVYSqDKLEAIIIRNKgeEAKSSLL 356 Clostridium spiroforme DSM 1552
ZP_05648907  331 VESVFKGvpGEIEVQVGSlGKQQAFIARKDgaEKIETYI 369 Enterococcus gallinarum EG2
ZP_06807288  353 ASSVFNNn-IEIQIQVVTaDGVRALLTRSKdaDTFNYVL 390 Aerococcus viridans ATCC 11563
ZP_07672053  334 LSIFSSNn-FKITVVVKAdDVDVATITRNKg-TSTTVAQ 370 Erysipelotrichaceae bacterium 3_1_53

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