Conserved Protein Domain Family
SPRY_RING
?
cd12883: SPRY_RING 
SPRY domain at N-terminus of Really Interesting New Gene (RING) finger domain
This SPRY domain is found at the N-terminus of RING finger domains which are present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. RING-finger domain is a type of Zn-finger that binds two Zn atoms and is identified in proteins with a wide range of functions such as viral replication, signal transduction, and development.
Links
?
Statistics
?
PSSM-Id: 293941
Aligned: 13 rows
Threshold Bit Score: 222.993
Created: 15-May-2012
Updated: 2-Oct-2020
Structure
?
Aligned Rows:
Download Cn3D
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
AAI34971  363 GVWYYEVTVITSGVMQIGWATKDSKFlNHEGYGIGDDEYSCAYDGCRQLIWYNARSKpHSHPCWKEGDAIGFLLDLskKQ 442 zebrafish
Q5R881    359 GVWYYEVTVVTSGVMQIGWATRDSKFlNHEGYGIGDDEYSCAYDGCRQLIWYNARSKpHIHPCWKEGDTVGFLLDLneKQ 438 Sumatran orangutan
BAE93335  349 GVWYYEVTIITPGVMQIGWATKKSKFfNYDGYGIGDDEYSCAYDGCRQLYWHQAQSRrHIHPAWREGDILGLLLDLekNQ 428 Ciona intestinalis
AAH80411  358 GVWYYEVTVITSGVMQIGWATKDSKFlNHEGYGIGDDEYSCAYDGCRQLIWYNAKSKpHQHPCWKEGDTVGFLLDLqkKL 437 African clawed frog
P90839    393 GVWYYEATVLTSGVMQIGLATKRSRFlNHEGYGIGDDASSVAYDGCRQLVWYNAKSHkHEHENWQPGDVIGVLLNIpeGE 472 Caenorhabditis ele...
EDV21654  294 GVWFYEVTVLTEGVMQIGWATKDSKFlNDEGLGVGDDEFSFGYDGCRQLLWHNAESCrHAHKRWTPGDVVGLLLDLnkGK 373 Trichoplax adhaerens
EFX69331  325 GIWYYEALIVTPGIMQIGWATKSSKFlNYEGYGIGDDEFSIAYDGCRNLIWYEAESIpHTLQQWKPGDILGCLLNIdrEE 404 common water flea
EDQ88443  497 GTWYYEVLLLTDGIMQVGWASQQCRYqAAEGFGIGDDEFSFSFDGARQLLWHDAQPQaCPLRRWRKGDVVGCYVDVerQM 576 Monosiga brevicoll...
EFA00412  437 GIWYYEVCIITPGVMQIGWATKNSNFlNHEGYGIGDDKYSLAYDGCRKLIWYNAKSEpQNLPAWQSGDILGCFLDLntPQ 516 red flour beetle
EGD75725  380 KCWYYEVTLFTAGIMQIGWAVDGCQYqTEEGRGIGDDEYSLAVDGSRQLVWFNQAPA-HTNIKWRPGDVLGCYLDLvhHR 458 Salpingoeca sp. AT...
EEN50252  267 GIWYYEVLVVTAGVMQIGWATKDSKFlNHEGYGIGDDEFSCAYDGCRQLIWYSAKSRpHAHEAWKEGDVLGFLLDLdnKQ 346 Florida lancelet
XP_781464 303 GVWYYEVRVITNGVMQIGWATKNSKFlNHEGFGIGDDEYSFSYDGCRQLYWYNAKSRtHRHPPWKSGDIVGFLLDLdkKY 382 purple urchin
KFZ53895  243 GVWYYEVTVVTSGVMQIGWATKDSKFlNHEGYGIGDDEYSCAYDGCRQLIWYNARSKpHSHPCWKEGDTIGFLLDLqeKQ 322 great crested grebe

AAI34971  443 MIFYLNGHQLPPEKqvff---satsGFFAAASFMSyQQCEFNFG 483 zebrafish
Q5R881    439 MIFFLNGNQLPPEKqvfs---stvsGFFAAASFMSyQQCEFNFG 479 Sumatran orangutan
BAE93335  429 VIFYLNGDPLPSEGgifn---hakeGFFAAASFMShQQCIFNFG 469 Ciona intestinalis
AAH80411  438 MIFSLNGCQLPPEKqvfs---satsGFFAAASFMSyQQCEFNFG 478 African clawed frog
P90839    473 VVFYLNGTPLKEPEteflsnrqpseGVFAAASFMSfQQCRFNFG 516 Caenorhabditis elegans
EDV21654  374 IYFYLNGVKCSETFrtk------kqGFYAAASLMEmQQAEFNFG 411 Trichoplax adhaerens
EFX69331  405 VIFSLNGVALGSNSqlfk---saksGFFAAASFMSfQQCEFNFG 445 common water flea
EDQ88443  577 MRFSVGGAHTEWMRlpeti--dasyGLYPAISLMTaQHVSFNFG 618 Monosiga brevicollis MX1
EFA00412  517 VIFSINGMRLPPCThvft---maqsGFFAAASFMSfQQCRFNFG 557 red flour beetle
EGD75725  459 AWFSVNGQRTRVLRlpph----lrdRVYPAASLMIdQHVAFNFG 498 Salpingoeca sp. ATCC50818
EEN50252  347 IIFSLNGNNLPPERdvfr---sarsGFFAAASFMSfQQCIFNFG 387 Florida lancelet
XP_781464 383 MAFSLNGNILPPESevfa---saqtGFFAAASFMSfQQCEFNFG 423 purple urchin
KFZ53895  323 MIFYLNGNQLPAEKqvfs---savsGFFAAASFMSyQQCEFNFG 363 great crested grebe
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap