2LXI


Conserved Protein Domain Family
RRM1_RBM10

?
cd12753: RRM1_RBM10 
Click on image for an interactive view with Cn3D
RNA recognition motif 1 (RRM1) found in vertebrate RNA-binding protein 10 (RBM10)
This subgroup corresponds to the RRM1 of RBM10, also termed G patch domain-containing protein 9, or RNA-binding protein S1-1 (S1-1), a paralog of putative tumor suppressor RNA-binding protein 5 (RBM5 or LUCA15 or H37). It may play an important role in mRNA generation, processing and degradation in several cell types. The rat homolog of human RBM10 is protein S1-1, a hypothetical RNA binding protein with poly(G) and poly(U) binding capabilities. RBM10 is structurally related to RBM5 and RNA-binding protein 6 (RBM6 or NY-LU-12 or g16 or DEF-3). It contains two RNA recognition motifs (RRMs), also termed RBDs (RNA binding domains) or RNPs (ribonucleoprotein domains), two C2H2-type zinc fingers, and a G-patch/D111 domain.
Statistics
?
PSSM-Id: 410147
Aligned: 6 rows
Threshold Bit Score: 162.029
Created: 17-Jan-2012
Updated: 25-Oct-2021
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
2LXI_A         1 SNIVMLRMLPQaATEDDIRGQLQSHGv-QAREVRLMRNKSSGQSRGFAFVEFShLQDATRWMEANQh------------s 67   human
CAG07342     199 SNIIMLRMLPPnATATEIRAQLQEQGi-QPREVRLMRNKSSGQSRGFAFVEFNvIQEATRWMETNQsytqwrnsflewgv 277  spotted green ...
XP_003216755 116 SSIIMLRMLPQsATENDIRGQLQAHGf-QPREVRLMRNKASGQSRGFAFVEFNhLQDATRWMEANQh------------s 182  green anole
P98175       128 SNIVMLRMLPQaATEDDIRGQLQSHGv-QAREVRLMRNKSSGQSRGFAFVEFShLQDATRWMEANQh------------s 194  human
XP_006004031 107 SNIIMLRMLPQsATENDIRGQLQAQGv-QAREVRLMRNKSSGQSRGFAFVEFNhMQDAVRWMEANQr------------s 173  coelacanth
XP_007888461 192 NRTIMLRGLPSsTTREDILELLKDYDgvQPKDVRVMRCKESGQSRGFAFVEFNhLQDATRWMEANQr------------h 259  elephant shark
2LXI_A        68 LNILGQKVSMHYSDPKP 84   human
CAG07342     278 LMILGQRVSMHYSDPKP 294  spotted green pufferfish
XP_003216755 183 LTILGQKVSMHYSDPKP 199  green anole
P98175       195 LNILGQKVSMHYSDPKP 211  human
XP_006004031 174 LTVLGQRVSMYYSDPKP 190  coelacanth
XP_007888461 260 LTILRRYVPMHYSTKPF 276  elephant shark
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap