2CPY


Conserved Protein Domain Family
RRM4_RBM12
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cd12749: RRM4_RBM12 
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RNA recognition motif 4 (RRM4) found in RNA-binding protein 12 (RBM12) and similar proteins
This subgroup corresponds to the RRM4 of RBM12, also termed SH3/WW domain anchor protein in the nucleus (SWAN), which is ubiquitously expressed. It contains five distinct RNA binding motifs (RRMs), also termed RBDs (RNA binding domains) or RNPs (ribonucleoprotein domains), two proline-rich regions, and several putative transmembrane domains. The biological role of RBM12 remains unclear.
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Statistics
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PSSM-Id: 410143
Aligned: 6 rows
Threshold Bit Score: 173.079
Created: 14-Sep-2011
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2CPY_A         17 CAHITNIPfSITKMDVLQFLEGip--vDENAVHVLVDNNGQGLGQALVQFKNEDDARKSERLHRKKLNGREAFVHVVTlE 94   human
NP_001079993  546 WGHLSNLPySIMRKDISHFFISegfaiDENFVQLLTDNNGQCIGQALVQFRSEDDARKSERLHRKKLNGRDVFLHIVNaE 625  African clawe...
NP_001003856  535 CAHITNIPyNVTKKDVRLFLDGie--lFEESLKVLVDSNGNGLGQAIVQFKSDEDALKAERLHRQKLNGRDAFVHLVTfD 612  zebrafish
AAP69823      546 CAHISNIPyNITKMEILQFLEGla--vEENSVQILVDNNGQGLGQALVQFKAEDDARKAERLHRKKLNGRDVVLRLITvE 623  chicken
XP_005986784  546 CAHIWNIPyNVTKNAVLQFFEGin--lEEDSVKVLVDSNGQGLGQAVVKFKSEADAVKAERLHRKKLNGRDAFLHLVTvD 623  coelacanth
XP_007910685  565 CGHIWNIPyNVTKSDVFQFLEGig--lAENGVHILTDNNGQGLGQALVQFLSEEEAQKAERLHRKKLNGRNAFVQLITlE 642  elephant shark

2CPY_A         95 DMREIEKNPP 104  human
NP_001079993  626 ERNDIELNPP 635  African clawed frog
NP_001003856  613 QMKEVERNPP 622  zebrafish
AAP69823      624 EMRDIERNPP 633  chicken
XP_005986784  624 EMKEMEKNPP 633  coelacanth
XP_007910685  643 QKHEMEKNPP 652  elephant shark
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