Conserved Protein Domain Family
RRM_LARP4

cd12707: RRM_LARP4

RNA recognition motif (RRM) found in vertebrate La-related protein 4 (LARP4)

This subgroup corresponds to the RRM of LARP4, a cytoplasmic factor that can bind poly(A) RNA and interact with poly(A) binding protein (PABP). It may play a role in promoting translation by stabilizing mRNA. LARP4 is structurally related to the La autoantigen. Like other La-related proteins (LARPs) family members, LARP4 contains a La motif (LAM) and an RNA recognition motif (RRM), also termed RBD (RNA binding domain) or RNP (ribonucleoprotein domain).

Links

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Source:	cd12430
Taxonomy:	Gnathostomata
PubMed:	5 links

Protein:	Representatives
	Specific Protein
	Related Protein
	Related Structure
	Architectures
Superfamily:	cl17169

Statistics

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PSSM-Id:	410106
Aligned:	5 rows
Threshold Bit Score:	169.855
Created:	10-Feb-2012
Updated:	25-Oct-2021

Structure

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PubMed References

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Sequence Alignment

include consensus sequence

Format: Row Display: Color Bits: Type Selection:

Q71RC2       199 CIVILREIPETTPIEEVKGLFksENCPKVISCEFAHNSNWYITFQSDTDAQQAFKYLREEVKTFQGKPIMARIKAIN 275 human
NP_001012718 199 CIIILREIPETTPVEEVKALFknENCPKVISCEFAHNNNWYVTFQSDTDAQQAFKYLREEVKTFQGKPIMARIKAIN 275 chicken
NP_001091246 203 CIIILREIPETTPLEEVKALFdnENCPKVISCEFAHNNNWYVTFQSDTDAQQAFRYLREEVKTFQDKPIMARIKAIN 279 African clawed frog
XP_007883031 201 CIIILREIPETTPVEDVQALFksENCPKVISCEFAHNNNWYITFQSDSDAQQAFKYLREEVKTFQGKPILARIKAKP 277 elephant shark
XP_014340251 255 CIIILREIPETTPVEEVEALFknGDCPKVIGCEFAHNNNWFITFQSDTDAQVAFKYLREEVKTFQGKPIMARIKANN 331 coelacanth

Citing CDD

Jiyao W et al.(2023). "The conserved domain database in 2023.", Nucleic Acids Res. 51(D1):D384-D388.

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