Conserved Protein Domain Family
RRM4_hnRPLL

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cd12705: RRM4_hnRPLL 
RNA recognition motif 4 (RRM4) found in vertebrate heterogeneous nuclear ribonucleoprotein L-like (hnRNP-LL)
The subgroup corresponds to the RRM4 of hnRNP-LL which plays a critical and unique role in the signal-induced regulation of CD45 and acts as a global regulator of alternative splicing in activated T cells. It is closely related in domain structure and sequence to heterogeneous nuclear ribonucleoprotein L (hnRNP-L), which is an abundant nuclear, multifunctional RNA-binding protein with three RNA-recognition motifs (RRMs), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain).
Statistics
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PSSM-Id: 410104
Aligned: 5 rows
Threshold Bit Score: 183.635
Created: 5-Jul-2012
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q8WVV9       452 PSCVLHYYNVPLcvTEETFTKLCNDhevltFIKYKVFDAKpsaKTLSGLLEWECKtDAVEALTALNHyqirvpngsnPYT 531 human
NP_001120904 441 PSCVLHYYNVPLsvEEEMFQKLCEDhevstFIKFKVFDAKpssKTLSGLLEWESKtEAVEALTVLNHyqirvpngsnPYT 520 western clawed ...
NP_001292580 453 PSCVLHYYNVPLcvTEETFVKLCEDhevlsFIKYKVFDPKpsaKTLSGLLEWECKtDAVEALTVLNHyqirvpngsnPYT 532 chicken
XP_014351133 448 PSCVLHYYNVPLsiTEETFHKLCEDhdvpdFIKYKVFAKHt-gKTLSGLLEWETKtEALEALTVLNHyqirvpngsnPYT 526 coelacanth
RXN23000     205 PSCVLHFYNVPPciSEDDLQRLCTEhdvpgFIKYKVFDAKpssKTISGLLEFDSKtHAVEVLTVLNHyqiripngsnPYT 284 rohu
Q8WVV9       532 LKLCF 536 human
NP_001120904 521 LKLCF 525 western clawed frog
NP_001292580 533 LKLCF 537 chicken
XP_014351133 527 LKLCF 531 coelacanth
RXN23000     285 LKLCF 289 rohu
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