Conserved Protein Domain Family
RRM_RBM20
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cd12685: RRM_RBM20 
RNA recognition motif (RRM) found in vertebrate RNA-binding protein 20 (RBM20)
This subfamily corresponds to the RRM of RBM20, an alternative splicing regulator associated with dilated cardiomyopathy (DCM). It contains only one copy of RNA-recognition motif (RRM), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain).
Links
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Statistics
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PSSM-Id: 410086
Aligned: 6 rows
Threshold Bit Score: 152.393
Created: 27-Sep-2011
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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putative RNA
Feature 1:putative RNA binding site [nucleic acid binding site]
Evidence:
  • Comment:Based on sequence similarity to Homo sapiens polypyrimidine tract binding protein.
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1            # ##                        # #  ### #                              #####
Q5T481        518 RVVHICNLPEGSCTENDVINLGLPFGKVTNYILMKSTNQAFLEMAYtEAAQAMVQYYQekSAVINGEKLLIRMSKR 593  human
CAG01297      278 SMAYAAAAAQGSCTENDVINLGLPFGKVTNYILMRSTHQAFLEMAYvEAAQAMVQYYQltPAMINNQKLLIRMSKR 353  spotted green puf...
KQK80315       40 RVVHICNLPEGSCTENDVINLGLPFGKVTNYILMKSTNQAFLEMAYsEAAQAMVQYYKekPAMINDDKLLIRMSKR 115  blue-fronted amazon
XP_014345592  514 RVVHICNLPEGSCTENDVINLGLPFGKVTNYILMRSTHQAFLEMAYtEAAQAMVQYYQqkPAMINEEKLLIRMSKR 589  coelacanth
OCT69697      290 HVVHICNIPEGSCNEKDVVNLGLPFGKVTNYILMKSTNQAFLEMAYtEAAEAMVQFYQekPAMINDEKLLIRMSKR 365  African clawed frog
XP_007901804  511 RVVHICNIPEGSCTESDVINLGLPFGKVTNYILMRATSQAFLEMAYpEAAQAMVQFYQqkPPVFSEQQLLVRMSKQ 586  elephant shark

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