Conserved Protein Domain Family
RRM3_MYEF2

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cd12662: RRM3_MYEF2 
RNA recognition motif 3 (RRM3) found in vertebrate myelin expression factor 2 (MEF-2)
This subgroup corresponds to the RRM3 of MEF-2, also termed MyEF-2 or MST156, a sequence-specific single-stranded DNA (ssDNA) binding protein that binds specifically to ssDNA derived from the proximal (MB1) element of the myelin basic protein (MBP) promoter and represses transcription of the MBP gene. MEF-2 contains three RNA recognition motifs (RRMs), also termed RBDs (RNA binding domains) or RNPs (ribonucleoprotein domains), which may be responsible for its ssDNA binding activity.
Statistics
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PSSM-Id: 410063
Aligned: 6 rows
Threshold Bit Score: 160.906
Created: 14-Sep-2011
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q9P2K5       524 QIFVRNLPFDLTWQKLKEKFSqCGHVMFAEIKMENGKSKGCGTVRFDsPESAEKACRIMNGiKISGREIDVRLDRNA 600 human
NP_001090142 597 QIFVRNLPFDLTWQKLKEKFNqCGRVMFAEIKMENGKSKGCGTVRFDcPETAEKACRLMNGmKINGREIDVRLDRNA 673 African clawed frog
NP_001012786 540 QIFVRNLPFDLTWQKLKEKFSqCGHVMFAEIKMENGKSKGCGTVRFDsPESAEKACRIMNGiKISGREIDVRLDRNA 616 chicken
AAI24098     251 QIFVRNLSYDLSWQKLKEKFShCGQVMYAEIKMENGKSKGCGTVRFDsPESAEKACRLMNGtKINGREVDVRLDRNA 327 zebrafish
XP_014345314 463 QIFVRNLPFDLTWQKLKDKFTqCGHVMFAEIKMENGKSKGCGTVRYDsPEAAEKACRIMNGiKISGREIDVRLDRIA 539 coelacanth
XP_007904166 551 QIFARNLPYDLPWQKLKEKFSqCGHVMFAEIKMENGMSKGCGTVLFDtPEAAEKACRLMNGtKITGREIDVRLDRNA 627 elephant shark
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