Conserved Protein Domain Family
RRM2_hnRNPA3

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cd12582: RRM2_hnRNPA3 
RNA recognition motif 2 (RRM2) found in heterogeneous nuclear ribonucleoprotein A3 (hnRNP A3) and similar proteins
This subgroup corresponds to the RRM2 of hnRNP A3, a novel RNA trafficking response element-binding protein that interacts with the hnRNP A2 response element (A2RE) independently of hnRNP A2 and participates in the trafficking of A2RE-containing RNA. hnRNP A3 can shuttle between the nucleus and the cytoplasm. It contains two RNA recognition motifs (RRMs), also termed RBDs (RNA binding domains) or RNPs (ribonucleoprotein domains), followed by a long glycine-rich region at the C-terminus.
Statistics
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PSSM-Id: 409996
Aligned: 6 rows
Threshold Bit Score: 158.577
Created: 20-Sep-2011
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P51991       126 KKIFVGGIKEDtEEYNLRDYFEkYGKIETIEVMEDRqsGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHNCEVKKALSKQ 205 human
AAI69881     118 KKIFVGGIKEDtEEYHLRDYFEgYGKIETIEVMEDRqsGKKRGFAFVTFDDHDTVDKIVVQKYHTINLHNCEVKKALSKQ 197 African clawed ...
ETE73685     104 KKIFVGGIKEDtEEYNLRDYFEkYGKIETIEVMEDRqsGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHNCEVKKALSKQ 183 king cobra
XP_007888252 103 KKIFVGGIKEDtEEYNLRDYFEkYGKIENIEVMTDRgsGKKRGFAFVTFDDHDSVDKIVVQKYHTVNGHNCEVRKALSRQ 182 elephant shark
XP_014349355 104 KKIFVGGIKEDtEEYHIREYFErFGKIETIEVMEDRgsGKKRGFAFVTFHDHDTVDKIVVQKYHTVNDHNCEVKKALSKQ 183 coelacanth
NP_001315077 104 KKIFVGGIKEDtEEYHIREYFEcYGKIETIDIMEERstGKKRGFCFVTFDDHDTVDKIVAQKYHTINSHNCEVRKALPKQ 183 zebrafish
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