2CPH


Conserved Protein Domain Family
RRM6_RBM19
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cd12571: RRM6_RBM19 
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RNA recognition motif 6 (RRM6) found in RNA-binding protein 19 (RBM19) and similar proteins
This subgroup corresponds to the RRM6 of RBM19, also termed RNA-binding domain-1 (RBD-1), which is a nucleolar protein conserved in eukaryotes. It is involved in ribosome biogenesis by processing rRNA. In addition, it is essential for preimplantation development. RBM19 has a unique domain organization containing 6 conserved RNA recognition motifs (RRMs), also termed RBDs (RNA binding domains) or RNPs (ribonucleoprotein domains).
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Statistics
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PSSM-Id: 409985
Aligned: 12 rows
Threshold Bit Score: 143.339
Created: 19-Sep-2011
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2CPH_A        16 SKILVRNIPFQANQREIRELFStFGELKTVRLPKKmtg-tgaHRGFGFVDFITKQDAKKAFNALChsTHLYGRRLVLEWA 94   house mouse
CAH65117     495 SKILVRNIPFQATVREIRELFStFGELKTVRLPKKmag-tgsHRGFGFVDFLTKQDAKKAFNALChsTHLYGRRLVLEWA 573  chicken
NP_001088073 797 SKILVRNVPFQATVREIRELFStFGELKTVRLPKKmag-tgsHRGFGFVDFVTKQDAKRAFSALChsTHLYGRRLVLEWA 875  African clawed...
AAI63877     804 SKILVRNIPFQATVKELRELFCtFGELKTVRLPKKgig--gsHRGFGFIDFLTKQDAKKAFSALChsTHLYGRRLVLEWA 881  zebrafish
XP_002612017 724 SKILVRNIPFQANKREVQNLFStFGEIKFVRLPQKfgg--tqHRGFGFVEFLSKQDAKRAFNALVhsTHLYGRRLVLEWA 801  Florida lancelet
EFX87687     728 SKLLVRNIPFEATTKEVTELFKpFGELKAVRLPKKmag-nqsHRGFAFIDFITKQDAKRAFESLSasTHLYGRRLVLEWA 806  common water flea
XP_002405304 497 TKILVRNIPFEATKKELQELFSvFGTLRDIRLPKKmag-tgrHRGFAFVDFLTKNDAKRAFQALCqsTHLYGRRLVLEWA 575  black-legged tick
NP_648337    785 TKILVRNIPFQAQYREVRDIFKaFGELRSLRIPKKattgedaHRGFGFVDYMSKAEAKRAFDALSasTHLYGRRLVLEWS 864  fruit fly
XP_002115715 209 TKILVKNLPFEATKSEVKQIFSvFGEIKCIRIPRKygq-rkqHRGFTFIEFITKADAKRAFTALQdsTHLYGRRLILQWA 287  Trichoplax adh...
NP_502432    748 TKLLVRNLPFEASVKEVETLFEtFGAVKTIRIPKKpgq-kqqHRGFGFVDFISADEAHRAFDSLVhsTHLYGRRLVLEWA 826  nematode
CBY24582     108 CKIMVRNVPFQCQVPELEQLFStFGELKFVRMPKNpt---gkHRGFAFVEFKLAADASSAFKALKlsTHIYGRRLVLEWA 184  Oikopleura dioica
XP_007900519 822 SKILVRNIPFQAKPKEVRELFStFGEIKTLRLPKKmgg-tgtHRGFGFVDFLTRQDAKKAFDALChsTHLYGRRLVLEWA 900  elephant shark
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