1WHW


Conserved Protein Domain Family
RRM3_RBM19
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cd12567: RRM3_RBM19 
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RNA recognition motif 3 (RRM3) found in RNA-binding protein 19 (RBM19) and similar proteins
This subgroup corresponds to the RRM3 of RBM19, also termed RNA-binding domain-1 (RBD-1), which is a nucleolar protein conserved in eukaryotes. It is involved in ribosome biogenesis by processing rRNA. In addition, it is essential for preimplantation development. RBM19 has a unique domain organization containing 6 conserved RNA recognition motifs (RRMs), also termed RBDs (RNA binding domains) or RNPs (ribonucleoprotein domains).
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Statistics
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PSSM-Id: 409983
Aligned: 11 rows
Threshold Bit Score: 159.095
Created: 22-Sep-2011
Updated: 17-Oct-2022
Structure
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Program:
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1WHW_A          7 GSGRLFVRNLSYTSSEEDLEKLFSaYGPLSELHYPIDSLTkkpKGFAFVTFMfPEHAVKAYAEvdgqvFQGRMLHVLPS 85   house mouse
CAH65117       76 ESGRLFVRNLPFTSTEEDLEKIFSkYGPLSEIHFPIDRLTkkpKGFAFITYMiPEHAVKAYAEmdgqvFQGRMMHLLPS 154  chicken
NP_001088073  384 ESGRLFVRNLPYSCTEDDLDKLFSkYGPISEIHFPIDSLTkkpKGFAFVTFLiTEHAVKAYAEvdgqiFQGRLLHVLPS 462  African clawed...
XP_001639550  361 ESGRLFLRNLAYSCSEEDIQHLFEkFGPLSEVNLPLDKHTnktIGIGFVTFLmPEHAVKAFNEldgtvFQGRLLHILPA 439  starlet sea an...
EFX87687      311 ESGRIFIRNLAYTATEEDIEALFSrYGPLAETHLPIDKHSrkiKGFAFVTYViPEHAVRAYTAldgtaFQGRMLHLIAG 389  common water flea
XP_002612017  263 ESGRLFIRNLPYLCKEEDLEGLFTkYGPLTECHIPIDTFTrraMGIAFVTFMlPEHAVTAFSQldgtvFMGRLLHILPG 341  Florida lancelet
NP_648337     362 ESGRIFFRNLAYTTTEEDLRKLFEqFGPVVEVNLPLDKLTrkiKGFGTVTYMmPEHALKAFNTldgtdFHGRLLHLLPS 440  fruit fly
EGD82752      501 ETGRIFVRNLAYVCTEDDIRALFEkFGPLSEVHMPLDTQTkkpKGIAFVTFLhPENAVKAFTQldasvFKGRLLHLLPA 579  Salpingoeca sp...
XP_007900519  410 DSGRLFVRNLPYTCTEEDLEKIFSkTGPIAEIHFPIDSLTkrpKGFAFVTYMiPEHAVKALAEidgevFQGRMLHILPS 488  elephant shark
XP_014346967  398 ESGRLFVRNLPYTCMEEDLEKMFSeYGPLSEVLFPIDSLTkkpKGFAFVTYMmPEHAVKAYAAldggvLQGRMIHILPS 476  coelacanth
AAP82506      396 ESGRLFIRNMPYTCTEEDLKEVFSkHGPLSEVLFPIDSLTkkpKGFAFVTYMiPENAVSALAQldgqtFQGRVLHVMAS 474  zebrafish
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