Conserved Protein Domain Family
RRM3_MEI2_fungi
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cd12532: RRM3_MEI2_fungi 
RNA recognition motif 3 (RRM3) found in fungal Mei2-like proteins
This subgroup corresponds to the RRM3 of fungal Mei2-like proteins. The Mei2 protein is an essential component of the switch from mitotic to meiotic growth in the fission yeast Schizosaccharomyces pombe. It is an RNA-binding protein that contains three RNA recognition motifs (RRMs), also termed RBDs (RNA binding domains) or RNPs (ribonucleoprotein domains). In the nucleus, S. pombe Mei2 stimulates meiosis upon binding a specific non-coding RNA through its C-terminal RRM motif.
Links
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Statistics
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PSSM-Id: 409949
Aligned: 7 rows
Threshold Bit Score: 153.334
Created: 20-Dec-2011
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
P08965                     596 RTTVMIKNIPNKftQQMLRDYIDVTNk-GTYDFLYLRIDFvn-------------------kCNVGYAFINFIepqSIIT 655 f...
WGS:AAHF:cds.AFUA_6G05280A 452 RTTIMLRNIPNKidQTMLKAIVDETSh-GKYDFMYLRIGEklhslfdckmkltlnfidfannCNVGYAFINFEdpiDIID 530 A...
CCA67564                   531 RTTVMLKNIPNKmsDSDLRKYISEVVp-NSFDFMYLRFDFns-------------------sANVGYAFVNFTevsALLA 590 P...
ABU82883                   644 RTTIMIKNIPNKftQQMLQEYIDATNp-KTYDFLYLRIDFrn-------------------rCNVGYAFVNFIdpiSIVT 703 P...
EEQ81691                   139 RTTCMIKNIPNKytQKMLINLLNEHHf-GCYDFVYLRMDFkn-------------------kCNVGYAFVNFTcteHIKT 198 N...
EIF46803                   111 RNTLLIRNIPNRvxFXDLKXTLDAVIkgEYEFLSDLRFDFen-------------------hCNVGYAFISFPkaeSIVK 171 D...
EHY64808                   148 RTTCMIKNIPNKlnIRQLIEVLTSICy-NAFDFVYLRMDFks-------------------nCNNGYAFINFRgakYIPI 207 N...

P08965                     656 FGKARVGTQWNvFHSEKICDISYANIQGKD 685 fission yeast
WGS:AAHF:cds.AFUA_6G05280A 531 FVKTRAGRSWNcFNSDKVAEVSYATIQGKD 560 Aspergillus fumigatus Af293
CCA67564                   591 FAKARLGVKWNmFCSEKVLQMSYANFQGKE 620 Piriformospora indica
ABU82883                   704 FGQARVGTKWNrFHSDKICDISYANIQGKE 733 Pneumocystis carinii
EEQ81691                   199 FYKKINNKGWKlFSSNKIAELTYASIQGFD 228 Nosema ceranae BRL01
EIF46803                   172 FYKEFQGKKWTkFNSEKICQLAYAKIQGKD 201 Dekkera bruxellensis AWRI1499
EHY64808                   208 FLDAIQGRKWKnFKSEKKGDIAYARIQGLH 237 Nematocida sp. 1 ERTm2
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