Conserved Protein Domain Family
RRM3_MEI2_like

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cd12531: RRM3_MEI2_like 
RNA recognition motif 3 (RRM3) found in plant Mei2-like proteins
This subgroup corresponds to the RRM3 of Mei2-like proteins, representing an ancient eukaryotic RNA-binding proteins family. Their corresponding Mei2-like genes appear to have arisen early in eukaryote evolution, been lost from some lineages such as Saccharomyces cerevisiae and metazoans, and diversified in the plant lineage. The plant Mei2-like genes may function in cell fate specification during development, rather than as stimulators of meiosis. Members in this family contain three RNA recognition motifs (RRMs), also termed RBDs (RNA binding domains) or RNPs (ribonucleoprotein domains). The C-terminal RRM (RRM3) is unique to Mei2-like proteins and is highly conserved between plants and fungi. To date, the intracellular localization, RNA target(s), cellular interactions and phosphorylation states of Mei2-like proteins in plants remain unclear.
Statistics
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PSSM-Id: 240975
Aligned: 15 rows
Threshold Bit Score: 159.483
Created: 20-Dec-2011
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q8W4I9        746 LMIKNIPNKYTSKMLLSAIDEHCKGt--YDFLYLPIDFKNKCNVGYAFINLIEPeKIVPFFKAFNGKKWEKF-NSEKVAT 822  thale cress
AAT38996      451 IMIKNIPNKYTSKMLLATIDEHHRGt--YDFLYLPIDFKNKCNVGYAFINMTSPtHIIPFYQAFNGKKWEKF-NSEKVAS 527  loblolly pine
XP_001700078  731 LMIKNIPNKYTQKMLLATIDEQFRGt--YDFFYLPIDFKNKCNVGYAFINMINPfDIIALVERFNNRRWERF-NSEKVCS 807  Chlamydomonas...
XP_001780082  469 LMIKNIPNKYTSKMLLAAIDEQHRGt--YDFIYLPIDFKNKCNVGYAFINMTSPaRIVPFYKAFNGKKWEKF-NSEKVAS 545  Physcomitrell...
XP_002670292  669 LMVKNIPNKYTQKMLLETVDVEFKTa--YDFFYLPIDFKNKCNVGYAFINFADPkLIIPFVERFNRKKWEKF-NSEKVCD 745  Naegleria gru...
XP_002982799  398 LMIKNIPNKYTSKMLLAAIDEQHRGt--YDFIYLPIDFKNKCNVGYAFINMLSPsLIVSFYQTFNGKKWEKF-NSEKVAS 474  Selaginella m...
EFN52088      859 LMVKNIPNKYTQKMLLALVEERFRGm--FDFFYLPIDFKNKCNVGYAFINMVRPeYIVPLVEELHGKKWPKF-NSEKICH 935  Chlorella var...
XP_002775654  145 VMIKNIPNKLTQQRMLKMIDDVSAQs--YDFFYLPIDLRNRCNVGYAFINFIEPtRIVPFYRAFHGTGWKNFnNSKKICD 222  Perkinsus mar...
XP_002291305    3 LMVRNIPNKYTQQMLLSEFSQAGHGpdkMDFFYLPIDFKNKCNRGYAFVNFVDFkDIIPFFDEYNGKGWKKF-NSDKICD 81   Thalassiosira...
Q9SJG8        682 LIIKNIPNKYTYKMLVAEIDEKHKGd--YDFLCLPTDFKNKCNMGHAFINMVSPlHIVPFQQTFNGKIWEKF-NSGKVAS 758  thale cress
Q8W4I9        823 LTYARIQGK 831  thale cress
AAT38996      528 LAYARIQGK 536  loblolly pine
XP_001700078  808 ISYARIQGR 816  Chlamydomonas reinhardtii
XP_001780082  546 LAYARIQGK 554  Physcomitrella patens subsp. patens
XP_002670292  746 ITYARIQGK 754  Naegleria gruberi strain NEG-M
XP_002982799  475 LAYARIQGK 483  Selaginella moellendorffii
EFN52088      936 IAYGRIQGK 944  Chlorella variabilis
XP_002775654  223 LSYARIQGK 231  Perkinsus marinus ATCC 50983
XP_002291305   82 ITYARIQGK 90   Thalassiosira pseudonana CCMP1335
Q9SJG8        759 LAYAEIQGK 767  thale cress
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