Conserved Protein Domain Family
RRM_XMAS2

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cd12457: RRM_XMAS2 
RNA recognition motif (RRM) found in X-linked male sterile 2 (Xmas-2) and similar proteins
This subfamily corresponds to the RRM in Xmas-2, the Drosophila homolog of yeast Sac3p protein, together with E(y)2, the Drosophila homologue of yeast Sus1p protein, forming an endogenous complex that is required in the regulation of mRNA transport and also involved in the efficient transcription regulation of the heat-shock protein 70 (hsp70) loci. All family members are found in insects and contain an N-terminal RNA recognition motif (RRM), also termed RBD (RNA binding domain) or RNP (ribonucleoprotein domain), followed by a PCI domain.
Statistics
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PSSM-Id: 409890
Aligned: 10 rows
Threshold Bit Score: 115.905
Created: 3-Aug-2012
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q9U3V9         12 KTLLCRNIPel-fLDKYVARSHFgRFGTLVNFVLRPRRMTCTVSYAsedEAARALLdgasFQGHLFDISYAD 82   fruit fly
EFN72987      127 NSITCTNVPkt-lLTKTAAKEYFiKFGNIVKITIRPKKCTIIVIYTtkqEANAAYYgssdYMGEKFHVEWTK 197  Camponotus floridanus
EFA02781       14 FTVKATDVPpeffITRDIAKRYFrRFGKVKLVTFRPKRNTLLIEYSnedGMLNALAvageYNGHMFNVIRDT 85   red flour beetle
EZA55012      127 HSITCSDVPka-lLTKTAAQHFFmSFGNIAKITIRPRRRSITVTYKtkkEAITAYKncgnYMDEEFHIEWTK 197  clonal raider ant
XP_015515125  134 KSITCTNVPeq-lLTKTAAKEYFtQFGQTAKIALKPRKTTITVYYTnraAANAAFHkagqFAGKMFDVSWTS 204  redheaded pine sawfly
TMW42992       17 KAISCEQIPel-fLDKIVAKKHFsKFGKIKRFILRPKRLSCTVEYEngeDAERAFMesgnFNGSEFIVNYAE 87   grey fleshfly
OXU28997      156 KSISCLDVPds-lLVKSVAKEYFeQFGEILKITIRPKRKIITVYYGtkvEASEAYNntgsFLGHDFKVEWTN 226  Trichomalopsis sarcop...
XP_018319008   14 CNISCTDVPle-lLDKFAARAHFrKFGHIVRIHLRPKSRSCQIEYTnqeSAQLASFagneYNGEEFNIVWGA 84   emerald ash borer
VEN34562       12 FKIICKDYPsefvLDKNVAKDYFrQFGKLKRVTFRPKLRICTVEYAnkeSCMNALSlggeYKGTKFEVMQNI 83   cowpea weevil
XP_022125374   25 FSITCSNVPeg-lFDSTAAKKHFsKFGKVHKIRLLPKKQICVVEYEqemPVERALLnagaYDGFMFDVTRTK 95   cabbage white
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