Conserved Protein Domain Family
RRM4_PTBPH3

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cd12426: RRM4_PTBPH3 
RNA recognition motif 4 (RRM4) found in plant polypyrimidine tract-binding protein homolog 3 (PTBPH3)
This subfamily corresponds to the RRM4 of PTBPH3. Although its biological roles remain unclear, PTBPH3 shows significant sequence similarity to polypyrimidine tract binding protein (PTB) that is an important negative regulator of alternative splicing in mammalian cells and also functions at several other aspects of mRNA metabolism, including mRNA localization, stabilization, polyadenylation, and translation. Like PTB, PTBPH3 contains four RNA recognition motifs (RRM), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain).
Statistics
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PSSM-Id: 409860
Aligned: 5 rows
Threshold Bit Score: 135.793
Created: 22-Sep-2011
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q6ICX4       348 RYCCSPTKMIHLSTLPqDVTEEEVMNHVQEHGAVVNTKVFEmnGKKQALVQFEnEEEAAEALVCKHATslgGSIIRISF 426 thale cress
ADE76165     374 RYCCSPTKMIHVSSLPgDVTEDDVISHLEEHGSIINSKLFEanGKKQALILFAnEEQATEALVCKHASaidGSTIRLSF 452 Sitka spruce
EFJ25475     325 KNCCPPSKILHISNVSdEVEEGDLLNFLAPHGVIQRVKLFEstNRRQALVEFDtIEQATEALASKHRSklkATSLRIAF 403 Selaginella moel...
XP_019577019 348 RYCCSPTKMIHLSTLPqDVTEEEVVNHVQEHGAIVNTKVFEmnGKKQALVQFEnEEEAAEALVCKHATslgGSIIRISF 426 Chinese rufous h...
PNR41096     341 RYCCAPTKMIHVSSLPaDIALEDITSHLSAHGTVANAKVFEsnGKKQALMLFEsEEQATEALVCKHASqlqSNTIRLAF 419 Physcomitrella p...
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