Conserved Protein Domain Family
RRM2_Nop13p_fungi

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cd12397: RRM2_Nop13p_fungi 
RNA recognition motif 2 (RRM2) found in yeast nucleolar protein 13 (Nop13p) and similar proteins
This subfamily corresponds to the RRM2 of Nop13p encoded by YNL175c from Saccharomyces cerevisiae. It shares high sequence similarity with nucleolar protein 12 (Nop12p). Both Nop12p and Nop13p are not essential for growth. However, unlike Nop12p that is localized to the nucleolus, Nop13p localizes primarily to the nucleolus but is also present in the nucleoplasm to a lesser extent. Nop13p contains two RNA recognition motifs (RRMs), also termed RBDs (RNA binding domains) or RNPs (ribonucleoprotein domains).
Statistics
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PSSM-Id: 409831
Aligned: 8 rows
Threshold Bit Score: 117.929
Created: 4-Feb-2012
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P53883       241 LFVGNLSFDVTDDLLRKHFqhc------------gdIVKIRMATFEDSGKCKGFAFIDFKneeGSTNALKdkscrkiagR 308 Saccharomyces c...
Q09100       230 LFVGNLDFETTDADLKEHFgqv------------gqIRRVRLMTFEDTGKCKGFGFVDFPdidTCMKAMElg------hN 291 Schizosaccharom...
CCA74974     194 LFIGNLSFETKEEEIAALFgrvhpklkkegesiedrLLRVRMGTFEDSGKCKGFAFVDFKtiqFATDALVnphnhslngR 273 Piriformospora ...
CAC28739     291 IFVGNLSFDTTEDDLRNHFdkc------------gaIRWVKVATFEDSGKCKGYGWVNFEegeAAQWAVKg-------fV 351 Neurospora cras...
EGX45211     224 IFVGNLRYEVTEQEIFRHFspa------------gkIKKVRFMTFEDSGKCKGFSWVDFEelkSAENVFSgki---egaE 288 Arthrobotrys ol...
RKP08860     121 LFVGNLPFEATKIDVQKVFapf------------gkIRKVRLMTFEDTGKCKGFAYVDYKeleGAKAAVEspqshylegR 188 Thamnocephalis ...
RPB11241     283 LFVGNLDFATTDEDLKSHFafa------------gpIQKIRLATFEDTGKCKGFGFVDFEdidSVKRAMLg--------L 342 Morchella conic...
XP_023897591 206 IFVGNLSFDVTVEDLTEHFaqa------------gaIEDVHMATFEDSGKCKGFAWVRFAeveSAEAAVKgfifkqpsdS 273 Quercus suber
P53883       309 PLRMEYGE 316 Saccharomyces cerevisiae S288c
Q09100       292 SWRLEYGE 299 Schizosaccharomyces pombe 972h-
CCA74974     274 ALVVEYAS 281 Piriformospora indica DSM 11827
CAC28739     352 KIREEIPE 359 Neurospora crassa OR74A
EGX45211     289 DSGDEKEE 296 Arthrobotrys oligospora ATCC 24927
RKP08860     189 RLRVEYGS 196 Thamnocephalis sphaerospora
RPB11241     343 SAEEEAAK 350 Morchella conica CCBAS932
XP_023897591 274 DVEDDADE 281 Quercus suber
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