Conserved Protein Domain Family
RRM1_Nop13p_fungi

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cd12396: RRM1_Nop13p_fungi 
RNA recognition motif 1 (RRM1) found in yeast nucleolar protein 13 (Nop13p) and similar proteins
This subfamily corresponds to the RRM1 of Nop13p encoded by YNL175c from Saccharomyces cerevisiae. It shares high sequence similarity with nucleolar protein 12 (Nop12p). Both, Nop12p and Nop13p, are not essential for growth. However, unlike Nop12p that is localized to the nucleolus, Nop13p localizes primarily to the nucleolus but is also present in the nucleoplasm to a lesser extent. Nop13p contains two RNA recognition motifs (RRMs), also termed RBDs (RNA binding domains) or RNPs (ribonucleoprotein domains).
Statistics
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PSSM-Id: 409830
Aligned: 7 rows
Threshold Bit Score: 117.556
Created: 4-Feb-2012
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P53883       127 VWIGNLSFdTTKDDLVRFFiaktkdned-----eksrvteqDITRLSMPrvaakn----snamknKGFCYMFFKnvEQMK 197 Saccharomyces c...
Q09100       107 IWVGNLSFhTTKEILTDFFvretsemikevseenikpitteQITRIHMPmskek-------rfqnKGFAYVDFAteDALK 179 Schizosaccharom...
EGD94402     141 VWIGNLPFtATREMLRTFLtsksg-------------ildsQITRVHIPdsgtkr----kgvkqnKGFAYVDFTsqEITA 203 Trichophyton to...
GAA98027     109 IWVGNMSYmTNESQLRQFFdv------------------cgEITRIHLPegkqk-------yevnRGFAYIDFEtaEATT 163 Mixia osmundae ...
CAC28739     163 VWIGNLRFtVTKSELKQWLvdnsgg-----------sitpeSITRVHMPtakaqpgqpkkekpenRGFAYVDFDslATKV 231 Neurospora cras...
XP_023919715  90 IWIGNLAFsVTKDALRQFFsdgl--------------ipetEITRIHMPtprpdpndrraikpqnRGFAYVDFSneDMLE 155 Quercus suber
CCJ31311      64 VWIGNLEFhTTRKDILNFFlekkpisn-------geeiqfhDITRIHIPkknk---------tenKGFAYVDFSslSAMK 127 Pneumocystis ji...
P53883       198 AVLELSEshLNGRNMLIKDS 217 Saccharomyces cerevisiae S288c
Q09100       180 LALQCSEkaLNGRNILIKSN 199 Schizosaccharomyces pombe 972h-
EGD94402     204 GGNPPSTkiFVGNLSFDTTK 223 Trichophyton tonsurans CBS 112818
GAA98027     164 KAIAMSEqnLIGRKLLIKDA 183 Mixia osmundae IAM 14324
CAC28739     232 AAIALSEteWYKRKLLIKDA 251 Neurospora crassa OR74A
XP_023919715 156 KAIALSEklLIGRRVLIKNA 175 Quercus suber
CCJ31311     128 ASLKRSEdvLNGRNLLIKDA 147 Pneumocystis jirovecii
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