2CQH,6FQ1


Conserved Protein Domain Family
RRM1_VICKZ

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cd12358: RRM1_VICKZ 
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RNA recognition motif 1 (RRM1) found in the VICKZ family proteins
Thid subfamily corresponds to the RRM1 of IGF2BPs (or IMPs) found in the VICKZ family that have been implicated in the post-transcriptional regulation of several different RNAs and in subcytoplasmic localization of mRNAs during embryogenesis. IGF2BPs are composed of two RNA recognition motifs (RRMs), also termed RBDs (RNA binding domains) or RNPs (ribonucleoprotein domains), and four hnRNP K homology (KH) domains.
Statistics
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PSSM-Id: 240804
Aligned: 9 rows
Threshold Bit Score: 85.1163
Created: 13-Sep-2011
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2CQH_A        11 LYIGNLSPavtADDLRQLFGDRKL-PLAGQVLLKs------GYAFVDYPDQNWAIRAIETLSgkvelhgKIMEVDYSVSK 83  human
Q9NZI8         4 LYIGNLNEsvtPADLEKVFAEHKI-SYSGQFLVKs------GYAFVDCPDEHWAMKAIETFSgkvelqgKRLEIEHSVPK 76  White-cheeked G...
CBY21364       4 LYIGNLSSdvsQELLHRELGDRAI-DVQNIVVNKr------GFAFIDLPDQVALDKAIEKLSglk-ingKEISVEHSVPR 75  Oikopleura dioica
XP_782196      4 LYVGKLSRdvtEDELRKLFEDNDI-PVQEILMKKn------GFAFVDVSNEELVEKATEKLNgyh-lqgGHIKVEPSVPR 75  purple urchin
XP_002411283   4 LYIGNLPAdvnEGSIRELFHEQTGaSPKSVLVKKg------GYAFVECADELAVGKAIEALNgdi-cleCLSLLLCALPG 76  black-legged tick
EFX66152       4 LYIGNLAAeanEAALRQLLQESGVgNVSSVLVKRg------GYAFIDCPEQSTVDRAIEKLNel----dARSTVAQKSLR 73  common water flea
EGI65425       4 LYVGNLPSdcnESALRQLFQEHSL-ACTTILVKRg------GYAFVDCADQSTADRAIDKLNg-----lYVIETELRHAI 71  Panamanian leaf...
XP_002737239   4 LYIGNLSSdvdDSVLGSLFEEHGV-VTTSVIVPRnengsirGYAFADCDSQGNAQKAIDKLNgyn-lqgQVIVVEYSTSK 81  Saccoglossus ko...
6FQ1_A         7 LYIGNLSEnaaPSDLESIFKDAKI-PVSGPFLVKt------GYAFVDCPDESWALKAIEALSgkielhgKPIEVEHSVPK 79  human
2CQH_A        84 K 84  human
Q9NZI8        77 K 77  White-cheeked Gibbon
CBY21364      76 T 76  Oikopleura dioica
XP_782196     76 K 76  purple urchin
XP_002411283  77 S 77  black-legged tick
EFX66152      74 K 74  common water flea
EGI65425      72 S 72  Panamanian leafcutter ant
XP_002737239  82 K 82  Saccoglossus kowalevskii
6FQ1_A        80 R 80  human
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