Conserved Protein Domain Family
RRM_Rrp7A
?
cd12294: RRM_Rrp7A 
RNA recognition motif in ribosomal RNA-processing protein 7 homolog A (Rrp7A) and similar proteins
This subfamily corresponds to the RRM of Rrp7A, also termed gastric cancer antigen Zg14, a homolog of yeast ribosomal RNA-processing protein 7 (Rrp7p), and mainly found in Metazoa. Rrp7p is an essential yeast protein involved in pre-rRNA processing and ribosome assembly, and is speculated to be required for correct assembly of rpS27 into the pre-ribosomal particle. In contrast, the cellular function of Rrp7A remains unclear currently. Rrp7A harbors an N-terminal RNA recognition motif (RRM), also termed RBD (RNA binding domain) or RNP (ribonucleoprotein domain), and a C-terminal Rrp7 domain.
Links
?
Statistics
?
PSSM-Id: 409735
Aligned: 19 rows
Threshold Bit Score: 113.182
Created: 14-Feb-2012
Updated: 25-Oct-2021
Structure
?
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
Q9Y3A4        59 RTLFVLNVPPYCtEESLSRLLStCGLVQSVELQekpdlaespkes---rskffhpkpvpGFQVAYVVFQKpSGVSAALAl 135 human
XP_002741084  46 RTLFVVNIPAYCnEECLQRLFSqCGTVESVHFQqkpgisktktave-estffkqvnlikGYKVAYVIFKNpSGLQNAKKf 124 Saccoglossus ko...
NP_608981     42 RTLFLLNVPPYVtEDSLRTVFGrAGSIEAVEFAakpgkeetikwyegtgepfsntrppfVFKVAYIVFEKnSSIGKALAl 121 fruit fly
XP_002109156  42 RTLFIINVPPYCtKNILRQIFSlFGEIDDIYQLrqpantipqyake-dssscfrrqlhtGFRVAYIVFKTpISLMKALKe 120 Trichoplax adha...
NP_001155371  42 QTLFVVGVPEFCdQKIMKHAFRrCGKVKSVFFHneptpiepeil----pskyfipksikGFKVAYVVFAHtSGLENALSm 117 pea aphid
ADD37895      50 RTLLVANVPPWAdKPSIKRLFVsNGAIDAVHFQkniesnsei---------egedqiieGFKFGFVVFERpSSLSRVIEs 120 salmon louse
ABX75473      42 KTLFVLNVPQYLnKNCFKFLYKhCGSIRSVFIHskpkgaeneas----nsifspsepnvGYKVAYVVFEEpSELSSALKc 117 Lycosa singorie...
EGI63889      48 RTLFVLNVPPYAtIDCLSNAFAnLCGNVQSVTFsd----------------------tkGFKTAYIVFKKeSSLDKAMEf 105 Panamanian leaf...
EEC11549      44 RTLFVVNVPPYCtEECLKRIFGdCGKVVKVWIQktpsaaakpdvg--tttffpnaspvtGFMVAYVVFLKeNSVKRALAl 121 black-legged tick
EAA01632      42 RTLYVLNVPPYAtEQALQHAFSsAGEIERVVLQekpsskesap-------iermdkdvfCFKVAYVVFAKpGALRKLLKt 114 Anopheles gambi...

Q9Y3A4       136 -----kGPLLVStesh--pvkSGIHKWISDY 159 human
XP_002741084 125 n---ykQPLLLStees--pifAGMKKWCKEY 150 Saccoglossus kowalevskii
NP_608981    122 k---siDLFNSSgec---ivkTGMELWHEEY 146 fruit fly
XP_002109156 121 scddtvVLANLEep-----plVGYKKWCQEY 146 Trichoplax adhaerens
NP_001155371 118 kc-tesEPFMLStqsa--pitNIVNRWCENY 145 pea aphid
ADD37895     121 md--ntKKYILStsth--pipVGLEKWKIMY 147 salmon louse
ABX75473     118 re-lptVPFKIInn------sVGLTKWIREY 141 Lycosa singoriensis
EGI63889     106 -----sKDFVITlksekstclTGLEKWCKEY 131 Panamanian leafcutter ant
EEC11549     122 s---vtEPRVLFpegs-paasVGLAKWCNEY 148 black-legged tick
EAA01632     115 k---siNALHTEerp----llTGVDKWTKAY 138 Anopheles gambiae str. PEST
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap