2RT3


Conserved Protein Domain Family
RRM2_4_MRN1

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cd12262: RRM2_4_MRN1 
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RNA recognition motif 2 (RRM2) and 4 (RRM4) found in RNA-binding protein MRN1 and similar proteins
This subgroup corresponds to the RRM2 and RRM4 of MRN1, also termed multicopy suppressor of RSC-NHP6 synthetic lethality protein 1, or post-transcriptional regulator of 69 kDa, and is an RNA-binding protein found in yeast. Although its specific biological role remains unclear, MRN1 might be involved in translational regulation. Members in this family contain four copies of conserved RNA recognition motif (RRM), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain).
Statistics
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PSSM-Id: 409706
Aligned: 6 rows
Threshold Bit Score: 124.048
Created: 13-Sep-2011
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2RT3_A     16 GACRNVFLGNLPn---------gITEDEIREDLEPFGPIDQIKIVTERNIAFVHFLNIaAAIKAVQELPl--NPKWSKRR 84   Schizosaccharomyc...
6226487   289 GATRNVYIGRMTiege----eshLSEEQLRVDLEEYGEIDCIKIIKEKGIAFIHFASIlNAIKVVTNLPi-rNPYYQNKR 363  baker's yeast
EAL70390 1008 SISRAIYIGNVSd---------nLPEKEIRKECEKYGEIESIRILRKKACAFVNFMNIpNATAALQTLNg-kKLGDTIVR 1077 Dictyostelium dis...
6226487   519 GASRNVYVGNIDfvgdslrdervFTESNLRHIFQQYGEVEQINFLPEKNCCFINYTNIsNAILALDKIKs--NPYFKDLK 596  baker's yeast
EIE88631  195 GATRSVYVGKLDk---------sILEQNITGQMVKYGAIEGVRMIKEKQCAFVDYLSIaSAVHCVSELPyakNWKSNPVR 265  Rhizopus oryzae R...
O13674    497 GASRNVYFSHISd---------sLTTEELELILRQYGEIESIKYLKNRSSGFVAYTNIsNAMKAVNGLPi--HPLFKKSK 565  Schizosaccharomyc...
2RT3_A     85 IYYGRDRC 92   Schizosaccharomyces pombe 972h-
6226487   364 IFYGKDRC 371  baker's yeast
EAL70390 1078 VNYGKVSQ 1085 Dictyostelium discoideum AX4
6226487   597 INFGKDRC 604  baker's yeast
EIE88631  266 FSKDPCVG 273  Rhizopus oryzae RA 99-880
O13674    566 IRYAPDRC 573  Schizosaccharomyces pombe 972h-
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