Conserved Protein Domain Family
RRM1_3_MRN1

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cd12261: RRM1_3_MRN1 
RNA recognition motif 1 (RRM1) and 3 (RRM3) found in RNA-binding protein MRN1 and similar proteins
This subfamily corresponds to the RRM1 and RRM3 of MRN1, also termed multicopy suppressor of RSC-NHP6 synthetic lethality protein 1, or post-transcriptional regulator of 69 kDa, which is an RNA-binding protein found in yeast. Although its specific biological role remains unclear, MRN1 might be involved in translational regulation. Members in this family contain four copies of conserved RNA recognition motif (RRM), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain).
Statistics
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PSSM-Id: 240707
Aligned: 21 rows
Threshold Bit Score: 74.1772
Created: 13-Sep-2011
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6226487      431 RTVYLGSLPKdvKIEEICNAVRgGLLQSIKLLnd------rYVCFVTFIDpTAAAQFYAMsslygFTVQKKRCKVGWGK 503 baker's yeast
EHA22963       2 RTVLIRNLPDriTHRDIVAAIKgGALLHIYLRar------eHMASVSFVEeAAARDFFRTtktygLIVAGKRVEVGWND 74  Aspergillus nige...
XP_002835970 194 RTLFFSRLPEkvTYTSFLGAIRgGMVVDAWMKpg------dHCGSISFLHsQSAEAFYRYakkndVYIDGRRVNVDWRE 266 Tuber melanospor...
EGU73438     164 RSVLLLNVPDgiTHGDVAAVIRgGPVLEIFLRsk------dNTATVSFLHeADACAFIENcrtagLYIKDRKIHTRWSD 236 Fusarium oxyspor...
EFY85603      53 RTVQLLNLPEgtTIADVTSIVRgGLLVNIYFRar------dNMVALSFLHsSDAHAFYQYvq-anGLYIKNTKVVPFGK 124 Metarhizium acri...
EHK47321       1 RSVRLVNLPEktTYGDIAGLIRgGSVYEFYITng------aATATITFVEvASAEAYFAHvrnngLFLKNKRIGIRWLQ 73  Trichoderma atro...
EHK21293       7 RSVQLLNIPEdaTYADITAVVRgGILFDISIMrr------sSTATVTFAEsSAAEAYYVHvrnncLYIKNKKASQASDR 79  Trichoderma vire...
EGE00564     165 RTVFLTKLPLdvDMRTLLSAIRgGAVYSAHIMnmqe-ysghHMGVVTFVRgKDASAYVNFatnhgVYFNDSRVDVYLSK 242 Trichophyton ton...
EHY51827     580 RTVMMDEIPVgtTMKDVLSMIRgGTLESLQLLppigratsfMTARVVFLHeGAADGMRARhqrvpFTINGTQVRVWKPI 658 Exophiala dermat...
EGP89706       1 RTLYFTGFPPrtTYEDLVSVIRgGKLLSINLRs-------eKSATVTFLDgAAEYLAWAKrn--dVYIHSKRIEVRWAE 70  Mycosphaerella g...
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