1AIW,1E6Z,1E6Z,1UR9,1H0G,1O6I,1E15,1OGB,1GOI,1E6N


Conserved Protein Domain Family
CBD_like
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cd12204: CBD_like 
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Cellulose-binding domain, chitinase and related proteins.
This group contains proteins related to the cellulose-binding domain of Erwinia chrysanthemi endoglucanase Z (EGZ) and Serratia marcescens chitinase B (ChiB). Gram negative plant parasite Erwinia chrysanthemi produces a variety of depolymerizing enzymes to metabolize pectin and cellulose on the host plant. Cellulase EGZ has a modular structure, with N-terminal catalytic domain linked to a C-terminal cellulose-binding domain (CBD). CBD mediates the secretion activity of EGZ. Chitinases allow certain bacteria to utilize chitin as a energy source. Typically, non-plant chitinases are of the glycosidase family 18.
Links
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Statistics
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PSSM-Id: 213176
Aligned: 40 rows
Threshold Bit Score: 55.41
Created: 6-Sep-2012
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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ligand bindingaromatic
Conserved site includes 2 residues -Click on image for an interactive view with Cn3D
Feature 1: ligand binding site [chemical binding site], 2 residue positions
Conserved feature residue pattern:[WY] TClick to see conserved feature residue pattern help
Evidence:
  • Structure:1E6N: Serratia marcescens inactive mutant binds N-acetylglucosamine pentamer; contacts at 4A
  • Structure:1E6Z: Serratia marcescens wildtype binds N-acetyl-d-glucosamine; contacts at 4A
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                                 ##                 
1AIW_A          5 ANANVYPnwvskdwaggqpTHNEAGQSIVYKGNLYTANW-YTA-SVPGSDs--SWTQVG 59   Dickeya dadantii 3937
1OGB_A        451 MTAPAYVp----------gTTYAQGALVSYQGYVWQTKWgYIT-SAPGSDs--AWLKVG 496  Serratia marcescens
1GOI_A        451 MTAPAYVp----------gTTYAQGALVSYQGYVWQTKWgYIT-SAPGSDs--AWLKVG 496  Serratia marcescens
1E6N_B        451 MTAPAYVp----------gTTYAQGALVSYQGYVWQTKWgYIT-SAPGSDs--AWLKVG 496  Serratia marcescens
ZP_09675873  1236 DGSVNYVp----------gNIYVEGDLVRYEGKTYQAKW-WTQ-SIPGSDd--SWKLVE 1280 Paenibacillus dendritiformis C454
YP_001886660  542 DGSVDYEe----------gSIYVEGDKVSYNGKMYEAKW-WTK-SIPGSDd--SWKLIA 586  Clostridium botulinum B str. Eklun...
ZP_08731379    83 AEQAKYPawk-------kgRTYVGGNKVLFNNKVYRAKW-WTRtGTPATSe--AWTLDV 131  Vibrio nigripulchritudo ATCC 27043
NP_578963      84 SSYPKYEp----------gKEYNQGDIVEYNGKLYKAKY-WTT-SPPSDDpygSWEYLG 130  Pyrococcus furiosus DSM 3638
6580045        82 SSYPKYEp----------gKTYNQGDVVEYNGKIWRVKY-WTQ-SVPGSDd--SWELVG 126  Pyrococcus kodakaraensis
ZP_07743401   822 PDADQYPawv-------qgNTYLGDDVVSHNSLVYKAKY-WTQ-TEPSATa-vEWTLMS 870  Vibrio sp. SP2010

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