2C7J,1KTP,1LIA,1B8D


Conserved Protein Domain Family
PE-PC-PEC_alpha
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cd12129: PE-PC-PEC_alpha 
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Alpha subunits of phycoerythrin, phycocyanin and phycoerythrocyanin; phycobilisome rod components
phycobilisomes (PBSs) are the main light-harvesting complex in cyanobacteria and red algae. In general, they consist of a central core and surrounding rods and function to harvest and channel light energy toward the photosynthetic reaction centers within the membrane. They are comprised of phycobiliproteins/chromophorylated proteins (PBPs) maintained together by linker polypeptides. PBPs have different numbers of chromophores, and the basic monomer component (alpha/beta heterodimers) can further oligomerize to ring-shaped trimers (heterohexamers) and hexamers (heterododecamers). Stacked PBP hexamers form both the core and the rods of the PBS; the core is mainly made up by allophycocyanin (APC) while the rods can be composed of the PBPs phycoerythrin (PE), phycocyanin (PC) and phycoerythrocyanin (PEC).
Links
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Statistics
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PSSM-Id: 271284
Aligned: 4 rows
Threshold Bit Score: 261.39
Created: 21-Oct-2011
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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chromophoreheterodimer
Conserved site includes 18 residues -Click on image for an interactive view with Cn3D
Feature 1:chromophore binding site [chemical binding site]
Evidence:
  • Comment:Conserved binding site (Cys-84) present in cyanobacterial and red algal phycobiliproteins, and in the beta-subunits of cryptophyte biliproteins. The actual position of the central conserved Cys varies from positions 81 to 84.
  • Citation:PMID 7783202
  • Structure:1KTP: Thermosynechococcus vulcanus C-phycocyanin alpha binds phycocyanobilin at position Cys-84; contacts at 4A
  • Structure:2C7J: Mastigocladus laminosus phycoerythrocyanin alpha binds biliverdin IX alpha at position Cys-84; contacts at 4A
  • Citation:PMID 6320870
  • Structure:1B8D: Griffithsia monilis R-phycoerythrin alpha binds phycoerythrobilin at position Cys-82; contacts at 4A
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                                               #     #       ##    # 
2C7J_A      2 KTPLTEAIAAADLrGSYLSNTELQAVFGRFNRARAGLEAARAFANNGKKWAEAAANHVYQKFPYTTQMQgpQYAstpEGK 81  Mastigocladus lami...
1KTP_A      2 KTPITEAIAAADTqGRFLSNTELQAVDGRFKRAVASMEAARALTNNAQSLIDGAAQAVYQKFPYTTTMQgsQYAstpEGK 81  Thermosynechococcu...
1LIA_A      2 KSVITTTISAADAaGRYPSTSDLQSVQGNIQRAAARLEAAEKLGSNHEAVVKEAGDACFSKYGYNKNPG--EAGenqEKI 79  Polysiphonia urceo...
1B8D_A      2 KSVITTTISAADAaGRFPSSSDLESIQGNIQRAAARLEAAQKLSGNHEAVVKEAGDACFAKYSYLKNAG--EAGdspEKI 79  Griffithsia monilis

Feature 1      ## ##  ##                  ##      #   # #   ##                                
2C7J_A     82 AKCVRDIDHYLRTISYCCVVGGTGPLDDYVVAGLKEFNSALGLSPSWYIAALEFVRDNHgl----tgDVAGEANTYINYA 157 Mastigocladus lami...
1KTP_A     82 AKCARDIGYYLRMITYCLVAGGTGPMDEYLIAGLSEINSTFDLSPSWYIEALKYIKANHgl----tgQAAVEANAYIDYA 157 Thermosynechococcu...
1LIA_A     80 NKCYRDIDHYMRLINYTLVVGGTGPLDEWGIAGAREVYRTLNLPSAAYIAAFVFTRDRLciprdmsaQAGVEFCTALDYL 159 Polysiphonia urceo...
1B8D_A     80 NKCYRDIDHYMRLINYSLVVGGTGPVDEWGIAGSREVYRALNLPGSAYIAAFTFTRDRLcvprdmssQAGVEFTSALDYV 159 Griffithsia monilis

Feature 1          
2C7J_A    158 INALS 162 Mastigocladus laminosus
1KTP_A    158 INALS 162 Thermosynechococcus vulcanus
1LIA_A    160 INSLS 164 Polysiphonia urceolata
1B8D_A    160 INSLC 164 Griffithsia monilis

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