1Y96


Conserved Protein Domain Family
Gemin6
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cd11676: Gemin6 
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Gemin 6
Gemins 6, together with the survival motor neuron (SMN) protein, other Gemins, and Unr-interacting protein (UNRIP) form the SMN complex, which plays an important role in the Sm core assembly reaction, by binding directly to the Sm proteins, as well as UsnRNAs. Gemin 6 forms a heterodimer with Gemin 7, which serve as a surrogate for the SmB-SmD3 dimer during the formation of the heptameric Sm ring.
Links
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Statistics
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PSSM-Id: 212487
Aligned: 20 rows
Threshold Bit Score: 71.9104
Created: 8-Feb-2012
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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heterodimer
Conserved site includes 26 residues -Click on image for an interactive view with Cn3D
Feature 1:heterodimer interface [polypeptide binding site]
Evidence:
  • Structure:1Y96; Human gemin6-gemin7 interactions, contacts at 4A
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1        ## ##  ##       ## # #    ######  # #                     ####### #        
1Y96_A         9 PLEWQDYIYKEVRVTASEkNEYKGWVLTTDPVSANIVLVNFled------------gsMSVTGIMGHAVQTVETM 71  human
EFN73444      19 PLLFMTYVGKEVKIMTKDkNVYYGIVYTLDPVSESIVLLHPqtd------------tqYHLKIIFNHAIKDIEVI 81  Camponotus floridanus
EFN79897      19 PILFNSYVGKEVKITMKDeDVHCGIVYTIDPVSESVVLLQPkep------------ttYSLKIVSGHSVKNIEII 81  Harpegnathos saltator
XP_001623692  15 LETFTNFTEKPVKILLSDnRTIEGWVFCVDPVSKSVILSQNte-------------gaWSNSVVLGHAIKHMEIQ 76  starlet sea anemone
XP_001601860  21 PILFKSYVNEKVTITTEDsNVHTGIVYTVDPVSESVVLMQPveg-----------eekMKMKILMRPAIQNIECS 84  jewel wasp
XP_002113600  10 LPDIIPYLHKKVKLQLIDgSSRTGCVYTIDPESLSIILFDNlld------------qqQQIKLIMGHAIVNITLL 72  Trichoplax adhaerens
XP_002433061  15 PIKLAQYVDKYAKITLITgKVLNGFVYTIDPVSQSVILISSekc-----------lekDNIKIIMDRSIKSMEIV 78  human body louse
XP_001415691  89 PAHLKALLGQEVLMTLSDgTTRQGTVYSLDPESFTIVLATGtdgvra-----ngslrdDACVIVPGHAVKAVEVV 158 Ostreococcus lucimar...
XP_003062778  23 TNHVKALIGQEVIITLGDaSTRMGIVYTVDPVNFSVALLKPrralikgqpasainlerDPLIVVPGHAIRGVEVV 97  Micromonas pusilla C...
XP_002123595  10 LDEKLSFLHQKVEVKLLNgKTEIGWVYTVDPIGHSIVILKE-----------------QKLTTIFGHSVKSVTII 67  Ciona intestinalis

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