Conserved Protein Domain Family
ChtBD1_1

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cd11618: ChtBD1_1 
Hevein or type 1 chitin binding domain; filamentous ascomycete subfamily
Hevein or type 1 chitin binding domain (ChtBD1), a lectin domain found in proteins from plants and fungi that bind N-acetylglucosamine, plant endochitinases, wound-induced proteins such as hevein, a major IgE-binding allergen in natural rubber latex, and the alpha subunit of Kluyveromyces lactis killer toxin. This domain is involved in the recognition and/or binding of chitin subunits; it typically occurs N-terminal to glycosyl hydrolase domains in chitinases, together with other carbohydrate-binding domains, or by itself in tandem-repeat arrangements.
Statistics
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PSSM-Id: 211316
Aligned: 14 rows
Threshold Bit Score: 48.5304
Created: 23-Feb-2012
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
carbohydrate
Feature 1:carbohydrate binding site [chemical binding site]
Evidence:
  • Comment:based on related proteins with structure
  • Comment:Sequence variations in the binding site can affect binding specificity and binding affinity.
  • Comment:Glycines stabilize the site and may not directly contact the substrate

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                  # ### #    #                
XP_384927     420 ECGSr--nGRTCAgs----glGNCCSANGYCGSTgSHCGq--gCQkgassACL 464  Gibberella zeae PH-1
XP_001394100  370 MCGG----NITCLgs----rfGPCCSGTGFCGSMsTFCGa--gCRpd-ngNCG 411  Aspergillus niger CBS 513.88
XP_384927      98 SCGGd--nKFVCGgs----tfGGCCSLQGWCGNStAHCGn--dCLpd-fgTCG 141  Gibberella zeae PH-1
XP_001404738   96 SCGA----TVLCGdw----edGDCCSAAGWCGKTaDYCGv--gCIh---gKCL 135  Magnaporthe grisea 70-15
XP_001904882  140 LCGPan-gDKTCAgs----gfGDCCSSGGWCGNTtDHCAa--sCQsg-fgTCD 184  Podospora anserina DSM 980
EDP49618      378 KCGK----DYTCAgs----sfGPCCSSSNYCGTSnLHCGf--gCQpe-agNCF 419  Aspergillus fumigatus A1163
XP_384322     361 TCGAk--nGLKCTgs----kwGNCCSHYNFCGSTsGYCDg--gCQsk-ygECN 404  Gibberella zeae PH-1
XP_001805211   55 MCGSv--sGQSCIgfngpaglSECCSPSGWCGNTdDYCGt--gCNpk-fgKCG 102  Phaeosphaeria nodorum SN15
XP_001551124  725 TCGTlfgsLYTCQgs----pnGNCCSRFGYCGREsDWCTg--gCVpa-fgICG 770  Botryotinia fuckeliana B05.10
XP_001790911  161 RCGKdf-aGASCDakg---ayGGCCSSYGYCGSTdGHCLvangCQn----GCK 205  Phaeosphaeria nodorum SN15

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