5GNJ


Conserved Protein Domain Family
bHLH_AtbHLH_like

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cd11393: bHLH_AtbHLH_like 
Click on image for an interactive view with Cn3D
basic helix-loop-helix (bHLH) domain found in Arabidopsis thaliana genes coding transcription factors and similar proteins
bHLH proteins are the second largest class of plant transcription factors that regulate transcription of genes that are involve in many essential physiological and developmental process. bHLH proteins are transcriptional regulators that are found in organisms from yeast to humans. The Arabidopsis bHLH proteins that have been characterized so far have roles in regulation of fruit dehiscence, cell development (carpel, anther and epidermal), phytochrome signaling, flavonoid biosynthesis, hormone signaling and stress responses.
Statistics
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PSSM-Id: 381399
View PSSM: cd11393
Aligned: 51 rows
Threshold Bit Score: 39.472
Threshold Setting Gi: 75309528
Created: 3-May-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
DNA bindingdimer interface
Conserved site includes 9 residues -Click on image for an interactive view with Cn3D
Feature 1:DNA binding site [nucleic acid binding site]
Evidence:
  • Comment:The N-terminal basic region of bHLH mediates high-affinity DNA-binding to specific hexanucleotide sequences
  • Structure:5GNJ; Arabidopsis thaliana MYC2 binds DNA, contacts at 4A
    View structure with Cn3D

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1     ##  ## ##   #                ##                      
5GNJ_G      9 HVEAERQRREKLNQRFYALRAVVPnvsKMDKASLLGDAIAYINELKSKVVKTE 61  thale cress
Q9SKX1     95 KRRRSNQRAPVVEEAAERLRNLVPgggGMETSKLMEETAHYIKCLSMQVKVMQ 147 thale cress
O81313    123 QTVVARRRRERISEKIRILKRIVPggaKMDTASMLDEAIRYTKFLKRQVRILQ 175 thale cress
Q9FMF4    265 GLSNEQSKKDKIRTALKILESVVPgakGNEALLLLDEAIDYLKLLKRDLISTE 317 thale cress
Q84RD0    168 QSIAARGRRRRIAEKTHELGKLIPggnKLNTAEMFQAAAKYVKFLQSQVGILQ 220 thale cress
Q9LRJ4    135 NDGGIITKRRKISDKIRSLEKLMPwerKMNLAMTLEESHKYIKFLQSQIASLR 187 thale cress
Q9SA82    139 QSIAARKRRRRITEKTQELGKLIPgsqKHNTAEMFNAAAKYVKFLQAQIEILQ 191 thale cress
Q9XIN0    460 NPRPRPKDRQMIQDRVKELREIIPngaKCSIDALLERTIKHMLFLQNVSKHSD 512 thale cress
Q7XJU1     34 LSFSSKERKDKLAERISALQQLVSpygKTDTASVLLEGMQYIQFLQEQVKVLS 86  thale cress
Q7XJU2     32 LSFSSKERKDKVGERISALQQIVSpygKTDTASVLLDAMHYIEFLHEQVKVLS 84  thale cress

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