Putative catalytic NodB homology domain of uncharacterized protein RC0012 from Rickettsia conorii and its bacterial homologs
This family contains an uncharacterized protein RC0012 from Rickettsia conorii and its bacterial homologs. Although their biochemical properties remain to be determined, members in this family seems to be composed of a seven-stranded barrel with detectable sequence similarity to the six-stranded barrel rhizobial NodB-like proteins, which remove N-linked or O-linked acetyl groups from cell wall polysaccharides and belong to the larger carbohydrate esterase 4 (CE4) superfamily.
Comment:based on similarity to other CE4 superfamily members
Comment:The Asp residue in the classical His-His-Asp zinc-binding motif of CE4 esterases is mutated to a hydrophobic residue (Leu or Met) in this subfamily.
Jiyao W et al.(2023). "The conserved domain database in 2023.",