Conserved Protein Domain Family
CE4_MJ0505_like

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cd10921: CE4_MJ0505_like 
Putative catalytic domain of uncharacterized protein MJ0505 from Methanocaldococcus jannaschii and similar proteins
This family contains an uncharacterized protein MJ0505 from Methanocaldococcus jannaschii and its prokaryotic homologs. Although their biochemical properties remain to be determined, members in this family is composed of a seven-stranded barrel with a detectable sequence similarity to the six-stranded barrel rhizobial NodB-like proteins, which remove N-linked or O-linked acetyl groups of cell wall polysaccharides and belong to a larger carbohydrate esterase 4 (CE4) superfamily.
Statistics
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PSSM-Id: 200547
Aligned: 7 rows
Threshold Bit Score: 317.414
Created: 31-May-2011
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
putative activeputative Zn
Feature 1:putative active site [active site]
Evidence:
  • Comment:based on similarity to other CE4 superfamily members

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                ##                                                                  #   
Q57928        35 EQKPIILIHDVSPVYfkeLKEIVKIIDKYHyqNRSYLFLIVNhan-----kynLKNYPEFVDYLHKLEKeGYHIEFHAYN 109 Methanocaldococ...
Q6LXR4        32 IFEPVILIHDVSPVYledLKEIDQVISKYGysKRTYLFLIVNhan-----eypLEENQDFVKYIRYLQTkGYNVELHGYD 106 Methanococcus m...
Q5JH22        54 SCRLVILVHDVSPVYlkeLKEITEIIDEYGmaNNTYFFVIPNhag-----khpIDKDPDFVNFLKESQAkGYHIELHGYM 128 Thermococcus ko...
NP_143815     30 NPQFIILIHDVSPVYsnyIQNITEIISTYNfqNSTILLVIPNhan-----ehpISGDPKFQALIRELEKeGYKVGIHGYN 104 Pyrococcus hori...
ABR56399      42 IKKPIILVHDVSPAYfnkLKKITSIIDKYNcsNNTILFVIPDlenpysggkwdLRKNKEFVDYLHQLEQrGYKIELHGYK 121 Methanococcus a...
NP_127452     26 TPKLIILVHDVSPVYypyIENITALIEEYGfqNSTILLIIPNhag-----khpISKDERFVQLIKKLEEeGYKVGIHGYD 100 Pyrococcus abys...
YP_004762449  61 NEPPLILVHDVTPYYfedIRQIIAVLDEYNcsNSTILFVIPVfdtthygdewsLRNHPDFVNYLHELQRrGYRVELHGYG 140 Thermococcus sp...
Feature 1        #                                      ###                                      
Q57928       110 HIddEFNCNKTVAEEKLNKSFKILEECGFnpkKIKYFIPPRYKlSEDAEKLFLGRNITIILENKMitekdgkiveisitn 189 Methanocaldococ...
Q6LXR4       107 HIecEFNCNCTLAMEKIEKSLEILNGLKId--GISCILPPRYGiSEDSKKAMLKKGFSIIVGQYAfemdngtvytynitn 184 Methanococcus m...
Q5JH22       129 HEyrEFDCDAGTARKKLELGLEELRALNF---SPSYFVPPNYAiSEDALKVVLSHNLSVITKDTLytpqgt---sykimn 202 Thermococcus ko...
NP_143815    105 HIgeEFNCDSETAKIKLSLAIEELNASNIt--FERIFLPPRYKiSKDPLNVLLENNFTVFLKDRIcypsgt---cirike 179 Pyrococcus hori...
ABR56399     122 HTyhEFNCSKSESSKKLHDAETIMSKCGFd--NMTLFLPPAWAlSNDSTYVILNHNYTIILTDKLiypngt---ikkitn 196 Methanococcus a...
NP_127452    101 HIgnEFLCNETIAEAKLRAAREELERAGIk--YDKVFVPPRYEiSTQALKVLLRNNFTVFLKGKVcypsgd---cerike 175 Pyrococcus abys...
YP_004762449 141 HTyhEFNCSYETANEKLDNATALMSSLGFs--NLTLFLPPAWAlNNESLRAILEHNLTVVMPNWLilpngt---rqriwn 215 Thermococcus sp...
Feature 1                                             #                     
Q57928       190 REYTWYLPKPLVKVAEKIATTDYKlsikenrKFFLSIHPKAVnYGSGLEFLDYFLNETS 248 Methanocaldococcus jannaschii
Q6LXR4       185 KEYTWYLEENNTLNEVNIAKEEYLes---eyKYFLSIHPKAVnYGGGIEFLDEFLDFTK 240 Methanococcus maripaludis
Q5JH22       203 REYTWYLSNSSAKFSLTLKRAKHDytr-crgTFYLSIHPKAVnYGAGLKFLREFLSFAV 260 Thermococcus kodakarensis KOD1
NP_143815    180 REYTWYTGKIRAKILLQVAKFEYTht---kgVFVLSVHPKAVnYGGGMYFLEEFLKYVR 235 Pyrococcus horikoshii OT3
ABR56399     197 NEYTWYIPKNEIEYRKHEALFDYKds---qyQFYISLHPEPVcYGGGLAILDYFLNKTR 252 Methanococcus aeolicus Nankai-3
NP_127452    176 REYTWYAGRLRAKIMLVIAKFEFTht---rgIFVLSIHPKAVnYGGGMDFLREFLKYAK 231 Pyrococcus abyssi GE5
YP_004762449 216 REYTWYIGESQVDDRLSVALHDYRktseegiPFYLSVHPGVVnYGGGLDFLRAFLRTTC 274 Thermococcus sp. 4557

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