Conserved Protein Domain Family
GIY-YIG_unchar_2
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cd10447: GIY-YIG_unchar_2 
GIY-YIG domain of uncharacterized hypothetical protein found in bacteria and archaea
The family includes a group of uncharacterized hypothetical proteins, mainly found in bacteria and a few found in archaea, with a GIY-YIG domain that shows statistically significant similarity to the N-terminal catalytic domains of GIY-YIG family of intron-encoded homing endonuclease I-TevI and catalytic GIY-YIG domain of nucleotide excision repair endonuclease UvrC.
Links
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Statistics
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PSSM-Id: 198394
Aligned: 63 rows
Threshold Bit Score: 67.2456
Created: 7-Oct-2010
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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putative activeputative metalGIY-YIG
Feature 1:putative active site [active site]
Evidence:
  • Comment:Based on similarity to the sequence of Enterobacteria phage T4 homing endonuclease I-Tevi (1LN0).
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1          #              # #        #   #                              #                
ADB41866      52 GIYLLLGKDeeg-qdqVYIGEAEt-iLKRLNQHLTqk--dfWNEAVIFVSKDenlnkaHIKYLESRLYEIAktanRYKIA 127 Spirosoma lingu...
CBA33520      74 GVYFLMGELseaglprAYIGQSGn-vGNRLVQHNQgk--dfWNRAMVVISLTnsmtqtHALFLEWIAIAEAtkagRYSLE 150 Curvibacter put...
ZP_07029049   54 GLYFLFGQSles-dpeLYIGQTGt-lRDRLKLHEKek--afWNRAVVIVTLTnrltqtHALFLEWRAINEAksvgRYSLV 129 Acidobacterium ...
YP_001097996  54 GIYFLIGDSdelerpeIYIGESEn-vLKRITEHTDnf---dWNSCICIVSLKnyfnkaFIKYLETRFILKAnl-sNCRVR 128 Methanococcus m...
YP_548771     53 GVYYLIGDDeekdqlsVYVGQTGa-lGKRLNEHDLdpkrefWNRALVAISLThsltqtHAMYLEWRSILQAnaaqRYSVE 131 Polaromonas sp....
ZP_04386078   52 GVYYLFGDDtdg-apkAYIGQSGn-vGARLQQHAAspkkefWTKAMVAVSLTnewtstHVAYIEWLSIDRAskadRYALQ 129 Rhodococcus ery...
AEG93235      57 ALYFLFGGAddgaeprVYIGQTGd-lRARLAAHHRdk--efWERALVLVSRTnsltntHALFLEWFCVQHArqagRYRDE 133 Ramlibacter tat...
ZP_08271314   53 GFYFLFGGDsk---deVYIGQSGn-lGSRLSQHSKddk-rdWERALAVVSLTnnltqtHVLYLESLSIERAkacdRYRVI 127 gamma proteobac...
YP_004419880  54 AVYFLIGGAdn---deVYIGQSGevgKRIERHHIEdk--kdWSRALVLISLTqnltqtHALYLEWLAIEKAkscqRFSLS 128 Gallibacterium ...
YP_001097149  50 GIYFLFGDSdelgkveTYIGESEq-vLKRLSEHKEtl---eWNSCVYILSSKnqfnkaYIKYLESQFISKAalskKVRLL 125 Methanococcus m...

Feature 1        #  
ADB41866     128 NTV 130 Spirosoma linguale DSM 74
CBA33520     151 NGN 153 Curvibacter putative symbiont of Hydra magnipapillata
ZP_07029049  130 NGN 132 Acidobacterium sp. MP5ACTX8
YP_001097996 129 NKN 131 Methanococcus maripaludis C5
YP_548771    132 NGN 134 Polaromonas sp. JS666
ZP_04386078  130 NGN 132 Rhodococcus erythropolis SK121
AEG93235     134 NGN 136 Ramlibacter tataouinensis TTB310
ZP_08271314  128 NGN 130 gamma proteobacterium IMCC3088
YP_004419880 129 NGN 131 Gallibacterium anatis UMN179
YP_001097149 126 NSY 128 Methanococcus maripaludis C5

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