2J72,2FHF,2J43,2J44,2J43,2J44


Conserved Protein Domain Family
CBM41_pullulanase
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cd10315: CBM41_pullulanase 
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Family 41 Carbohydrate-Binding Module from pullulanase-like enzymes
Pullulanases (EC 3.2.1.41) are a group of starch-debranching enzymes, catalyzing the hydrolysis of the alpha-1,6-glucosidic linkages of alpha-glucans, preferentially pullulan. Pullulan is a polysaccharide in which alpha-1,4 linked maltotriosyl units are combined via an alpha-1,6 linkage. These enzymes are of importance in the starch industry, where they are used to hydrolyze amylopectin starch. Pullulanases consist of multiple distinct domains, including a catalytic domain belonging to the glycoside hydrolase (GH) family 13 and carbohydrate-binding modules (CBM), including CBM41.
Links
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Statistics
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PSSM-Id: 199215
Aligned: 107 rows
Threshold Bit Score: 56.1865
Created: 7-Jun-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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carbohydrate
Conserved site includes 5 residues -Click on image for an interactive view with Cn3D
Feature 1:carbohydrate binding site [chemical binding site]
Evidence:
  • Structure:2J44; Streptococcus virulence factor with bounf carbohydrate, contacts 4A
  • Structure:2J72_B, Thermotoga maritima N-terminal family 41 CRM binds to Maltotetraose (M4), contacts at 4A.
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                             # #                                                         
2J72_B          4 TTIVVHYHRydg-kyDGWNLWIWpvepv--------------------sqegkAYQFtg--eDDFGKVAVVKLpmd-ltK 59   Thermotoga ma...
2J44_A        110 GTVRVNYYRtdg-nyDKKSLWYWgdvknps-----------------saqwpdGTDFta--tGKYGRYIDIPLnea-arE 168  Streptococcus...
2J44_A          2 NYFRIHVKKlpeenkDAQGLWTWddvekps-----------------enwpngALSFkdakkDDYGYYLDVKLkgeqakK 64   Streptococcus...
ADV68370      154 GVARLHYHRpdg-qyDGWGLHAWedttat-------------------vewskPLPPtg--tDAFGAYWDVPLkad-waK 210  Deinococcus m...
ADI14147       32 DTARIHYNRpdg-dyEGWTLHVWedtses-------------------vtwesGLTPtg--eSDFGLYWDVGLveg-aeT 88   Truepera radi...
YP_003684814  143 SKARIHYFRpdg-nyAGWGLHLWedtleq-------------------vewskPFPPtg--qDDYGLYWDFRLkeg-akK 199  Meiothermus s...
YP_002786221   25 NVARVHYQRadh-ayAGWGLHAWedtavs-------------------vdwakPIAQag--rSDWGAYFDIPLkag-aqK 81   Deinococcus d...
ADV68370       50 NVLRVRYVRpdg-qyTGWGLHVWedttaa-------------------vewakPLAPtg--iDANGAYWDVPLkag-aaK 106  Deinococcus m...
YP_002136594   34 DNVTLHYHRadg-syDGWALHSWesfqakseasdewaakqmsdrplkgvtwfkPMQPag--kDDFGVFWTIPAaefengR 110  Anaeromyxobac...
ZP_08401794    35 DSVSLHYYRpdg-nyAGWGVHFWesfekvqdgqvvgak-tksdapimgitwgnPMQPtg--kDGFGVYWQVPAnefrngK 110  Rubrivivax be...

Feature 1            #         #     #                          
2J72_B         60 VGIIVRLne-wqAKDVAk-DRFIEIk-dGKAEVWILQgvEEIFYEK 102  Thermotoga maritima
2J44_A        169 FGFLLLDeskgdVKIRKe-NYKFTDl-kNHSQIFLKDddESIYTNP 212  Streptococcus pneumoniae
2J44_A         65 ISFLINNta--gKNLTG--DKSVEKlvpKMNEAWLDQd-YKVFSYE 105  Streptococcus pneumoniae
ADV68370      211 LSFIVHKg---dEKDPGa-DMRLERt--AGNQGWIVSgqDQVYTQK 250  Deinococcus maricopensis DSM 21211
ADI14147       89 LGFIVHRg---dDKDPGp-DQFLNLt--ESREAWILSgdPTVYTTL 128  Truepera radiovictrix DSM 17093
YP_003684814  200 VGFIVHKg---dEKDPGp-DMFLLLd-qHGREVWVLSgsTRIYTQR 240  Meiothermus silvanus DSM 9946
YP_002786221   82 VGIIVHKg---dQKDHNv-DLWFDLs--RGRELFVKSgsTLVAYAK 121  Deinococcus deserti VCD115
ADV68370      107 VGFIVHNg---dEKDPGa-DLFADPg--QGREVLVRSgvADFTYVT 146  Deinococcus maricopensis DSM 21211
YP_002136594  111 VNYIIHKg---dKKDQCnkDMFWMIk--DSKEAWVVSgdCKVYLSK 151  Anaeromyxobacter sp. K
ZP_08401794   111 INYIIHRg---dSKDCVk-DSAWFLp--QGRQIFINQgdCTAYLTL 150  Rubrivivax benzoatilyticus JA2

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