2KPP,3LD7


Conserved Protein Domain Family
Lin0431_like
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cd09911: Lin0431_like 
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Listerrria innocua Lin0431 is similar to the N-Utilization Substance G (NusG) N terminal (NGN) insert (DII)
This family contains domains homologous to Listeria innocua Lin0431, a protein that is similar to the N-Utilization Substance G (NusG) N terminal (NGN) insert (domain II, DII). Lin0431 and Aquifex aeolicus NusG DII (AaeNusG DII ) have similar structure and similar basic charged surface distributions that may bind negatively charged nucleic acids and/or another anionic binding partner, suggesting a possible role in transcription/translation regulating functions. Despite these two domains having low sequence similarity, the NusG DII and DUF1312 domain families may have diverged from common evolutionary ancestral proteins, and may have similar biochemical functions.
Links
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Statistics
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PSSM-Id: 197365
Aligned: 84 rows
Threshold Bit Score: 88.6738
Created: 23-Feb-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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trimer
Conserved site includes 8 residues -Click on image for an interactive view with Cn3D
Feature 1:trimer interface [polypeptide binding site]
Evidence:
  • Comment:Lin0431 is a domain of unknown function
  • Structure:3LD7, Listeria innocua Lin0431 trimer interface, contacts at 4.0A
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                ######        ##                                                        
2KPP_A         8 VVAIISQNGKVIREIPLtghkgNEQFTIKGkg---aQYNLMEVDGERIRIKEDNSPDQVGVKMGWKSKAGDTIVCLPHKV 84  Listeria innocua
3LD7_A         8 VVAIISQNGKVIREIPLtghkgNEQFTIKGkg---aQYNLXEVDGERIRIKEDNSPDQVGVKXGWKSKAGDTIVCLPHKV 84  Listeria innocua
ZP_02075974   32 SQVVIYVDQKEIGRYDLd---tDTTKEIQTa----kGTNTLVIENGMAYVTDADCPDQVCIRMGKISKTGENIVCLPHKL 104 Clostridium sp....
ZP_02207789   42 NTADVYIDDKLVQTIDLs---vDDEYTFQTd----kGSNTVEVRNGAVSMKSADCPDKVCVRMGTKNRNGETITCLPHKL 114 Coprococcus eut...
ZP_05344573   34 GYAVISSGGEEAARLPLs---eNTELVIGDee---qGYNRIVVEDGAISVTEADCPDKVCVREGKISRTGEFIACLPHEL 107 Bryantella form...
YP_001382778  35 AVAVIKQNGKIIEKVDLskvkeKRQLKINYndkdhkGYNVIEIDKGSIRFIDADCPDKVCIKSGVLKKPGETAACLPHKL 114 Clostridium bot...
Q896H8        35 KIAVIKQDGKIIKKINLstidkTETFLIKSkn--gnDDNNVKIEKGKVSILEATCPDQVCVKAGPISEPGDTLVCLPNKL 112 Clostridium tetani
YP_002473198  46 RIALIKQDGKLIKTINLstvknSEEFIIKYkd---nDFNKIKVEKGRIRITDANCPDKICVKKGWISKPGENIVCLPHRL 122 Clostridium klu...
ZP_02422578   38 HTACIYSNGRLIRTVELds-esEQTFTVYSdg---gGYNVIKVSGGAISVSDADCPDKICVKTAPVSDGIQPIVCMPHKL 113 Eubacterium sir...
ZP_05391098   35 HIASIKQDGKVIKTIDLdt--iKEKQEIKVpyn-gnHFNIIEILPGKIRIKDADCPDKICVKTGWISEPGQSSVCLPHRL 111 Clostridium car...

Feature 1                
2KPP_A        85 FVEIKSTQ 92  Listeria innocua
3LD7_A        85 FVEIKSTQ 92  Listeria innocua
ZP_02075974  105 VIQVEGDV 112 Clostridium sp. L2-50
ZP_02207789  115 VIEVHGGQ 122 Coprococcus eutactus ATCC 27759
ZP_05344573  108 IITIEGGG 115 Bryantella formatexigens DSM 14469
YP_001382778 115 IITIEKND 122 Clostridium botulinum A str. ATCC 19397
Q896H8       113 IIVIEGKT 120 Clostridium tetani
YP_002473198 123 IISIDGKN 130 Clostridium kluyveri NBRC 12016
ZP_02422578  114 VIRVEARR 121 Eubacterium siraeum DSM 15702
ZP_05391098  112 MITIEGKN 119 Clostridium carboxidivorans P7

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