Conserved Protein Domain Family
Csx17_I-U
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cd09767: Csx17_I-U 
CRISPR/Cas system-associated protein Csx17
CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins; Predicted subunit of the Cascade complex;
Links
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Statistics
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PSSM-Id: 187705
Aligned: 7 rows
Threshold Bit Score: 733.463
Created: 13-Apr-2011
Updated: 17-Jan-2013
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
YP_002514506  24 LKALGVLRLVCEQVDATAKGWWQDE----------CFMLRTRLDDNDLRRFFIEDYRPTPMLSPWNGGSGFyrkgnet-a 92   Thioalkalivibr...
CBE69811       4 LKALGILRLVSEQKDEDACGWWKNDvfwlrspvlfKEAATEEAKRDALVKFFLEEYKPTPIVAPWAGGSGFfrkdnk--- 80   NC10 bacterium...
YP_003186041  19 LKAMAVLRLLAEQRDPDVRGYWHQD----------VFCIQTELSPDQLVDFFLRTYRPTPIMAPWNGGGGFirgknr--- 85   Alicyclobacill...
YP_306589     19 LKALGVFKIFSQQKDNNARAYWKNN----------IFVINAEYDAAAMTNFFLHEYAPSPLFRPWGGRSGFykgsseksa 88   Methanosarcina...
YP_003198485  18 LKGLAVFRLVAEQKDPDVTAWWDKG----------TFRVHTRLAPEELTSFFCEQYTPTPIITPWNGGSSFypgdnt--- 84   Desulfohalobiu...
ZP_02929518   18 LKALGVFRLVSDSADGDAFATASWKn--------dSLQITSRFDREDLLRFFLNNYQPTPIVAPWNGGSGFyegdeq--- 86   Verrucomicrobi...
ZP_01089597   26 ILRAISACAALEDRDPDAEGWWSLDda------afMIRSSRYPDAASLVKFFAEKYQPTPIIAAWNKSGGVtnk------ 93   Blastopirellul...

YP_002514506  93 wstlekIITTQAERWRPFRDTAEVMADALEHLk----------------------------------------------- 125  Thioalkalivibr...
CBE69811      81 -kaveaLGKSKTPRIRLYAKVIQSIQAIIEEEk----------------------------------------------- 112  NC10 bacterium...
YP_003186041  86 -epvdwLRNTSGERFRPYRDALQAVDRVFAGTp----------------------------------------------- 117  Alicyclobacill...
YP_306589     89 realrpLIDSKDSRFDSLRKVYDAFQKFSDSKg----------------------------------------------- 121  Methanosarcina...
YP_003198485  85 -egleaIVQTGDSRFRIYKEAIEAVSSWPEWGknvntvrelmaalqgmisssnpgkkqdelftlqnnitnlaek-----v 158  Desulfohalobiu...
ZP_02929518   87 -savesIQNSTSPRFGELKRDIATILQWSQLGptkqafsimvarlkeveakldgkaakdigdlvsdfyhsladfisevgi 165  Verrucomicrobi...
ZP_01089597   94 ---ievAILCLSGDVSQFRADHEAMLEASGLKktkklskvgalkfalsdaa----------------------------- 141  Blastopirellul...

YP_002514506 126 ---------------------------------------lTEKPAELDKr------------------------------ 136  Thioalkalivibr...
CBE69811     113 ---------------------------------------iGDKPKKGDKt------------------------------ 123  NC10 bacterium...
YP_003186041 118 ---------------------------------------lTDKPKDEDKv------------------------------ 128  Alicyclobacill...
YP_306589    122 ---------------------------------------iTEKPSGDKLv------------------------------ 132  Methanosarcina...
YP_003198485 159 ktteggdplgmrlvdlssrasekaevykqlwntakkartvYTKDIREQTkk----------------------------- 209  Desulfohalobiu...
ZP_02929518  166 tedlvlawhieqaegfdvgsnqttkkaksnlikaakkvrtKFKQLHRASgk----------------------------- 216  Verrucomicrobi...
ZP_01089597  142 ----------------------hlddlkkqatvaglvcsyKEKRTRGKVttevtiastveplerfrreqsvplaelgfsv 199  Blastopirellul...

YP_002514506     --------------------------------------------------------------------------------      Thioalkalivibr...
CBE69811         --------------------------------------------------------------------------------      NC10 bacterium...
YP_003186041     --------------------------------------------------------------------------------      Alicyclobacill...
YP_306589        --------------------------------------------------------------------------------      Methanosarcina...
YP_003198485     --------------------------------------------------------------------------------      Desulfohalobiu...
ZP_02929518      --------------------------------------------------------------------------------      Verrucomicrobi...
ZP_01089597  200 tknlsndgqlkfstnssnrsnverliadfnaslsdgsrdagsdgntksqtsngplyaeisakesgtdgtlpkiermsmdp 279  Blastopirellul...

YP_002514506 137 ---------------------------aLLARLRATLDDEFLPWLDAAV-LLTDDKPDYPPLLGTGGNDGRLDFTSNYMQ 188  Thioalkalivibr...
CBE69811     124 ---------------------------rLIRRYRRELPDDVIGWMDAAM-VLWQDGQGFAPLLGTGGNDGRFDFSQNFML 175  NC10 bacterium...
YP_003186041 129 ---------------------------aLLARLRAELPDEAVEWLDAVA-AITADRLGFAPIYGTGGNDGNFEFTNNFMQ 180  Alicyclobacill...
YP_306589    133 ---------------------------eFLEDLRAQLPEDILEWLDTCY-VLTGNNRKYLPLLGTGGNEGSGNYSSNYLQ 184  Methanosarcina...
YP_003198485 210 ---------------------------iILPLCRSRLPDACLEWLDALCaIHADGEISYHQVLGSGGNDARLDFGNNFMK 262  Desulfohalobiu...
ZP_02929518  217 --------------------------eeIILLARSSLSDVALSGIDAMVpLLNEGQVAYPPLFGSGGTDGRLEFTNKYLQ 270  Verrucomicrobi...
ZP_01089597  280 vllrclalarewvnelqtqgalrndsinILAQYRDNLPTQVTEAFDAIS-ICHLIRRNDNPLFVNRGQQGRTDVFRMNWE 358  Blastopirellul...

YP_002514506 189 RLLEMFdpv-tgkAQGdv-gNKLESALFARPVP----GMTALAIGQFSPGAAGGPNSSTGFDSGAQVNIWDYVLMLEGAL 262  Thioalkalivibr...
CBE69811     176 RLVTLGihn--agPDSra-aRWLDNALFGDPIA----GLTAAAVGQFAPGRAGGPNATQGMQGDATDNPWDFVLMIEGAL 248  NC10 bacterium...
YP_003186041 181 RLREMFqpd--gtPTDva-eRLLRAALFEEPVN----GLLNVSIGQFQPGQNGGPNAGPGFEASRRVNPWDFIFSLEGGI 253  Alicyclobacill...
YP_306589    185 ALTEVLvkk--keKESk---QLLEHSLFSKHTP----KLSNLSFGQLSPGAVAEANSTEGYRSTSKLVNPWDVIFSIEGT 255  Methanosarcina...
YP_003198485 263 KISALLl-----gSDQsasrKFLSASLWGTSVE----GLPKTKIGQFDPGRAGGYNQGMGIEAKDFTASPWDFILTIEGT 333  Desulfohalobiu...
ZP_02929518  271 CLCEVIdpktglpTVDa--aTWLETSLFQETTSg---PLSEAPIGQFFPGAAGGANSKSGFGGGSTVNPWDFIFMMDGGM 345  Verrucomicrobi...
ZP_01089597  359 HFIEFRn------APD----VFTQSSLFGERITtghtGSVKGKGTPFFPDVIKSYNQGLDWVTEDLPFCPLDYLLAVEGA 428  Blastopirellul...

YP_002514506 263 LFAATATRRLESADp-----SALSYPFTVRPSGGGSGAVAl----------gDERPARAEIWMPLWERPASLPELRVLLG 327  Thioalkalivibr...
CBE69811     249 LLGGAAVRRLGVGLd-----SKSAFPFTVRSSMAGFASSSd----------sDAATGRGEIWLPLWSRPARLAELRVLFG 313  NC10 bacterium...
YP_003186041 254 LFSAAAARKFGRQH------TDFTYPFTVRAASGGQGAMSvs---------dEGQKARAETWLPLWRRPASLPELEQFLQ 318  Alicyclobacill...
YP_306589    256 TLFAGSASKRFGGSqggfgsNFGAFPFTVLPSVAGTGNITfkdnfkdpnkksDYKTFDSEFWLPLWNRPTSYNEITYLFH 335  Methanosarcina...
YP_003198485 334 LLLASSVGKRQGVSt----gSTLTSPFTVRFSPVGFTSNVy----------tEPEGPETEIWMPLWNQPARYGEIKQLFS 399  Desulfohalobiu...
ZP_02929518  346 MFAGSAAKRFESDGd-----AFLVCPFCVGHNGIGFGSSSr----------sDEAKAGCEIWAPLWERPATFGELKAVFS 410  Verrucomicrobi...
ZP_01089597  429 FAMRGSVSKSLGARs----qAYAAFPFVFEGPESMTDDQG------------DVTGLGASLWFPIWTRPATFGELHSFIL 492  Blastopirellul...

YP_002514506 328 EGRVTLNG-------RLPRDGLDFARAVAKLGTDRGVRAFQRYAFMMRSGKAYLATPLNRFHVHRNPKADLIDQLERGDW 400  Thioalkalivibr...
CBE69811     314 EGRAEVTG-------RQARDGVDFVRAVASLGVDRGVQQFIRLSFLKRSGKAFLAAPLGRVLVRQQESVDLLRQLDPWLD 386  NC10 bacterium...
YP_003186041 319 EGRAQVRSrlmsvgwRPARTGVDFARACAELGIDRGVDSFQRYAFLERYGRMYYAVPLSRFHVRRRPEADVLDDLDRWLT 398  Alicyclobacill...
YP_306589    336 EGRAQVGR-------RKANNGLDFVRAISSLGVDRGIDAFVRYGRLKRQGSGKNANALAIPLGTFKVRQQKNVNLIEELD 408  Methanosarcina...
YP_003198485 400 EGRCSIGK-------RQAKSGLEFSRAVGTLGVDRGITAFERYGFLKRRGENKVALPAGKIAVRFKPSLELVNELDPLLS 472  Desulfohalobiu...
ZP_02929518  411 EGRAQLRG-------GRVQNGVDFAQAAVTLGVDRGISEFQRYAILERNGQSNFATPLGRFAARRNARVDLLADVQKWMS 483  Verrucomicrobi...
ZP_01089597  493 DSQARLPK-------KDCRFSSDFIRAIRSQGVDAGFTAFQEFRFKMKGARIPWAVTGQFVTCSTTTSASLLNEFLAPVD 565  Blastopirellul...

YP_002514506 401 LRr-----FRRAARST----HAPARLQGLAHRLDDALFDLVRVADPRRVQEVLKVLGEVQFYLAls------pSLREQVR 465  Thioalkalivibr...
CBE69811     387 RFr-----RACADNNA----PPRFKAALRNIEKAIFEFCRYGGPTFFQAIDVALGRAERELALSag------kVGKRTTS 451  NC10 bacterium...
YP_003186041 399 QVq-----SLPSMEEP----PLSALSALRRVEDAVFDLCQHGGAHRVRELIVAVAQLDRVVSRRa--------DLRERVE 461  Alicyclobacill...
YP_306589    409 NWln--vlRDKCSSKEs--vAARYSSSLRSIEEAIFSFSKHGNISDFQNLLIELGKAERSFASA---------GANRPIR 475  Methanosarcina...
YP_003198485 473 KLd----qFLRAFKKP----PTSFLQARQKIDQNIFNCTLQPDPVQFLKIVRSLGQMEKRIALRdr------dKDPKLPQ 538  Desulfohalobiu...
ZP_02929518  484 RLr----iKTDSQSKPk--aPNGVRSAFNVVERRIMELCQKDSPDHLQSLLAALGSTERAVARSfnwasekdkFQRENIS 557  Verrucomicrobi...
ZP_01089597  566 ASgflnqfRFRTPREVkrdrKPDLHPYRAPILEAIETAAVEPSSTKIIDVLSKLATLNTQLAQSkalr--ekvSGGRVTF 643  Blastopirellul...

YP_002514506 466 PVPRLDAHWVEAARDd----SHEFRVAAALAGLDDGLPMGVH----------LAPIDPVKRNVWApes-------rlAVW 524  Thioalkalivibr...
CBE69811     452 PIVGLSADWIAAANDn----TTEFEIALALAGIYDGNGKIGWlranlepvvvWRGDNGGLAAKWAekd-------raVVW 520  NC10 bacterium...
YP_003186041 462 PLALASQAWIEQAWPqdareQAEFSLGLAIGTMRDVGEISHRey------faPVVLHERRTWQWVsdeemp-sarvrLAF 534  Alicyclobacill...
YP_306589    476 PLNDLSPSWINACDDe----SVEFRIACAVASIYDKKIGSIRrq------lePSEINNKGRLKWSetr-------ssVVW 538  Methanosarcina...
YP_003198485 539 PLFGLSPQWIIKSDDg----SPETRIAAALASIHSTGKVGPIrs-------nMAGVRAQAPWHWEdrd-------sqQHW 600  Desulfohalobiu...
ZP_02929518  558 PLRGLRQDWLEKIGD-----SAETRLAASLAGARVSFGKGREtlwf---rqhLEPLKRSEKRGWFnpmwselssendVTW 629  Verrucomicrobi...
ZP_01089597  644 VPPLRCDDWSSALQDlq--vDPEFEIAWALASICGHEKQPDGtssqvepflgSLIPLRRLGEKWVlpempd-ppspqAVW 720  Blastopirellul...

YP_002514506 525 GQGNLSDNLAQVLQRRLLTASRtdlnd----------------------------kplsgRCPADEGAVaAFLAGDADER 576  Thioalkalivibr...
CBE69811     521 NSANLSANLAAVLRRRLVDGERngcpn----------------------------lplaaHNFASLNTVsRFLAGELDER 572  NC10 bacterium...
YP_003186041 535 DSPDLVRCLLTLAERRLLDEERlrqrkdesegaqdrkhqegksedksklkskigfhsrrePFAARLEHLvPFWFGETRDA 614  Alicyclobacill...
YP_306589    539 SNTDLCSNMKAILQRRILEEKMkgsnf----------------------------tpiggKVAVSLSDIgRFIRGEVNDK 590  Methanosarcina...
YP_003198485 601 FGSDLTEKLGNVLTYRLMDAERksvsn----------------------------ipfmgNLELSPYDVmPFLHQETKDD 652  Desulfohalobiu...
ZP_02929518  630 HEGDLADSLNAILTRRIQRVENagaeg----------------------------wpdwsPRYASLADItAFIEQRTDDL 681  Verrucomicrobi...
ZP_01089597  721 TGIDLARDLSSVLARRVLDSAKdfrp------------------------------aivgTCTAQLTSIlRFLQGELDDR 770  Blastopirellul...

YP_002514506 577 RIAELMAGLACAr----LPARLPLRQrga------seaSSLPMIY--ALLKPLFVPDAQLREAGVLTPDGClplpp---- 640  Thioalkalivibr...
CBE69811     573 RIEDLLWGLMLL-----PQPPGILSRpad------danAPLPRAF--ALLKLLLLPQPLTVNGLSVTIKTEss------- 632  NC10 bacterium...
YP_003186041 615 RILDYAWAFSAYr----GDAPSVLHQdgardvrgeatpAWIPYLY--ALLRLTFTSERELRRALESVSRRDlgqppvved 688  Alicyclobacill...
YP_306589    591 KISDLIWGLSIIkwkyyNKERHGVDWnng-------idVMIPRAY--AFLKLIFIPGNLIFENQRWEISYDekkgihl-- 659  Methanosarcina...
YP_003198485 653 LLEDLLWGFTLI-----NWRKSGIQSirnkwe-kptqqTVLSRTW--CLLKLLHHPNKIKGHSFKREKSIS--------- 715  Desulfohalobiu...
ZP_02929518  682 LLADLIWGLCLLdw-qsIAQRERMARlaaetv-eqpanTSLELEEepPRQEIDQVPDFDWRSDEEVRHQVVpssfyallk 759  Verrucomicrobi...
ZP_01089597  771 RIARLVEALSLIdw-rySAAHTVVNKsfsde---evdwDSVPIAYa-AARSLIEVACEKRRTEAAEIEDRSgprtk---- 841  Blastopirellul...

YP_002514506 641 ------------alprlLRAGPAGv---GRAVDLARRRRRASGLAD 671  Thioalkalivibrio sp. HL-EbGR7
CBE69811     633 ---------------iaALLTAGHv---GEVCRIAMRRLRASGLSP 660  NC10 bacterium 'Dutch sediment'
YP_003186041 689 f-------slpvprevlALLGADRpanaVRAREVLERRFLASGLAP 727  Alicyclobacillus acidocaldarius subsp. acidocald...
YP_306589    660 ----------pslpevlRVIDTQQ----DKAFELVTRRLKSSGLTP 691  Methanosarcina barkeri str. Fusaro
YP_003198485 716 -----------------HLLQAHRv---DEACNKATQRLRISNLHP 741  Desulfohalobium retbaense DSM 5692
ZP_02929518  760 lcfrrkdrdgkvvpivsAIHQRARmgdgLAASRLAARRLLASGEVP 805  Verrucomicrobium spinosum DSM 4136
ZP_01089597  842 ------------vqrtvALLSRQEprlaALATTDALRRLAIVGVPN 875  Blastopirellula marina DSM 3645
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