3KG4


Conserved Protein Domain Family
Cas5_I-C
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cd09752: Cas5_I-C 
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CRISPR/Cas system-associated RAMP superfamily protein Cas5
CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family
Links
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Statistics
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PSSM-Id: 187534
Aligned: 45 rows
Threshold Bit Score: 252.911
Created: 11-Jan-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3KG4_A         7 IRLHIWGDYACFTRPEMKv--ERVSYDVITPSAARGILSAIHWKPAINWVIDKIYVLKPIrfesvrrnelgakiseskvs 84  Mannheimia succ...
NP_241203      5 VQFELFGDYALFTDPLTKiggEKLSYSVPTYQALKGIAESIYWKPTIVFVIDELRVMKPIqmeskgvr------------ 72  Bacillus halodu...
YP_597015      7 FYVRVSGQRALFTNPATKggsERSSYSVPTRQALNGIVDAIYYKPTFTNIVTEVKVINQIqtelqgvr------------ 74  Streptococcus p...
YP_001812652   5 IEFKVYGEYALFTDPLTKlggEKMSYQVPTYQAIKGIVESIYWKPTILIVVDAIRIMHPIkmeakgmr------------ 72  Exiguobacterium...
YP_001278622   7 VTFKVWGRYALFTDPLTRiggEKYSYQVPTYEALKGILSSVYWKPTIVWIIDKVRVMKPIrtqprsvk------------ 74  Roseiflexus sp....
YP_001319499   7 VEFKVSGRYALFSDPINRiggEKFSYQVPTYQALKGILESVYWKPTLIWIIDEVRVMNLIktqsqnirpvnf-------- 78  Alkaliphilus me...
Q9KFY3         5 VQFELFGDYALFTDPLTKiggEKLSYSVPTYQALKGIAESIYWKPTIVFVIDELRVMKPIqmeskgvr------------ 72  Bacillus halodu...
NP_269632      7 FYVRVSGQRALFTNPATKggsERSSYSVPTRQALNGIVDAIYYKPTFTNIVTEVKVINQIqtelqgvr------------ 74  Streptococcus p...
Q3ARV4         5 IEFKVYGREAMFTDPVSRiggEKCSYHIPTYEALKGIVKSIYWKPTIIWVVDKVRVMKPIrtktkclk------------ 72  Chlorobium chlo...
YP_910048      8 IEYEVWGRYALFSEVATRvggEKYSYQVPTYQALKGITESIYWKPTFKWVIDAVRVMNKIqtesrgvrti---------- 77  Bifidobacterium...

3KG4_A        85 gamkrksvadlytvieddRQQRAATVLKDVAYVIEAHAVMtskag--vdentTKHIEMFKRRALKGQCFQQPCMGVREFP 162 Mannheimia succ...
NP_241203     73 -----------pieygggNTLAHYTYLKDVHYQVKAHFEFnlhrpdlafdrnEGKHYSILQRSLKAGGRRDIFLGARECQ 141 Bacillus halodu...
YP_597015     75 -----------allhdysADLSYVSYLSDVVYLIKFHFVWnedrkdlnsdrlPAKHEAIMERSIRKGGRRDVFLGTRECL 143 Streptococcus p...
YP_001812652  73 -----------pieygggNSLAHYTYLRDVCYHVRAHFEFnenrpdlvfdrnEGKHYSIMKRSLEAGGRRDIFLGARECQ 141 Exiguobacterium...
YP_001278622  75 ----------plkyhasgNDLAIYTYLADVEYQVQAHFEWnknrpdlehdrnEHKHHSVARRMIDRGGRRDVFLGTRECQ 144 Roseiflexus sp....
YP_001319499  79 -------sgtskgtgtplNTLSIYTYLTNVEYQVKAHFEWnynrpnlekdrnENKHYIVAKRMINRGGRRDVFLGTRECQ 151 Alkaliphilus me...
Q9KFY3        73 -----------pieygggNTLAHYTYLKDVHYQVKAHFEFnlhrpdlafdrnEGKHYSILQRSLKAGGRRDIFLGARECQ 141 Bacillus halodu...
NP_269632     75 -----------allhdysADLSYVSYLSDVVYLIKFHFVWnedrkdlnsdrlPAKHEAIMERSIRKGGRRDVFLGTRECL 143 Streptococcus p...
Q3ARV4        73 ----------plkyhekgNSLAIYNYLCDVEYQVLAHFEWnlhrpelaqdciNGKHYSVALRALDKGGRQDIFLGTRECQ 142 Chlorobium chlo...
YP_910048     78 --------vyqpkkknvkNDLSYYTYLKDVRYQVLAHFEWndlreeladdrdENKHHNIAMRSVRQGGRRDIFLGARECQ 149 Bifidobacterium...

3KG4_A       163 AHFALIddndplplsqlsesefnrDLGWMLHDIDfeh-----gntPHFFRAELKNGVIDVP 218 Mannheimia succiniciproducens MBEL55E
NP_241203    142 GYVAPCefgsgdgf---ydgqgkyHLGTMVHGFNypdetgqhqldVRLWSAVMENGYIQFP 199 Bacillus halodurans C-125
YP_597015    144 GLLDDIsqeeyettv-syyngvniDLGIMFHSFAypkdk-ktplkSYFTKTVMKNGVITFK 202 Streptococcus pyogenes MGAS9429
YP_001812652 142 AYVEPIdfdsdds----fydgadlHFGTMVHGFDypdetgrdelaVRLWNPVMKDGVIAFP 198 Exiguobacterium sibiricum 255-15
YP_001278622 145 GYVEPCkfgegegf---ydnygelSLGVMFHGFDypdeykpgefwARFWRATMKDGIITFP 202 Roseiflexus sp. RS-1
YP_001319499 152 AYVEPCkfgegega---ydhygslSFGLMFHGFDypdetgedkltARLWSPVMNNGYIKFL 209 Alkaliphilus metalliredigens QYMF
Q9KFY3       142 GYVAPCefgsgdgf---ydgqgkyHLGTMVHGFNypdetgqhqldVRLWSAVMENGYIQFP 199 Bacillus halodurans
NP_269632    144 GLVDDIsqeeyettv-syyngvniDLGIMFHSFAypk------dkKTPLKSYFTKTVMKNG 197 Streptococcus pyogenes M1 GAS
Q3ARV4       143 GYVEPCkfgegkge---ydniselAFGFTFHGFDypd-----etgQKMFRSRFWNPKMVKG 195 Chlorobium chlorochromatii CaD3
YP_910048    150 AYVEPCefgggegf---ydsygewNMGYMFHGFSypd-----enpDHNLISRFWMPIMKDG 202 Bifidobacterium adolescentis ATCC ...
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