Conserved Protein Domain Family
Cas8c_I-C
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cd09713: Cas8c_I-C 
CRISPR/Cas system-associated protein Cas8c
CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-C subtype; also known as Csx13_N family
Links
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Statistics
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PSSM-Id: 187844
Aligned: 4 rows
Threshold Bit Score: 417.704
Created: 7-Feb-2010
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
EAW36791      10 LHFNLSEPNFTILHCLGLAGLAMSLKQIEKQYPLpaq-----rpGKLNWCVDSRNIDLYWQGQD-SLALDWLFKESFKID 83  Lyngbya sp. PCC...
jgi:Ava_3491  10 IQLNLGDPSMTLLHRAGVAGLWMTLKKLEKIYPTpae-----riGNLTWLLTPHYINLDWEGQD-FTVLDWLLKQSFQIS 83  Anabaena variab...
AAN50389      18 VFQRGLSECTSPLLRAGLAGLYSTLYSLKDEKKP----------KTLSWELTQDSIQITSKGEF-SKDFQWIINHGYQTK 86  Leptospira inte...
P38586        45 LSIRLYAPGMTPLLRAGAGGLAASLRAILGSASPaapwpspvrlGPGTATVEQEAIHLDWGGKApEATLRALFGASFRVK 124 Myxococcus xant...

EAW36791      84 qRGLISFTGLNPESMPLPT---QIVNHQCLTnSSFLQHNKFFKS--GGVASE----SITVDEIPIEVKY-KRAVSYAHQN 153 Lyngbya sp. PCC...
jgi:Ava_3491  84 dEGLISLTGLDSQNMDIQN---QIIIHQGIT-ATFTQHNKFFKS--AGQQSK----QLIIDGIQVRVDY-KKAASYAHQH 152 Anabaena variab...
AAN50389      87 -EGIFYCPGIHRTKTIHKD---RMHFHNAMM-GTFLQHGRIQVRtkGAGTAVsiedECKLLYFPLLVEEkKIKYRKDAES 161 Leptospira inte...
P38586       125 -QGFIDLPGTRPPGAPEPPpelAAALHDALK-VTFLQHGKSTQG--GARRRV----TFEVDARPVIVES-QGYDSFVHQT 195 Myxococcus xant...

EAW36791     154 FAPKICDPqgnLYQEPIQIVSWLYPGAIVRhaaAEkSTKIEETVEQAIALLYAPVACIYYLVRsrihnQKAQYAVVIPVI 233 Lyngbya sp. PCC...
jgi:Ava_3491 153 FAKHLCDQygqLLKEPIGIRGWLYPGAVVRhyaFKeQTAFEEKAEYALALLFAPMACQYFVLRshtepSHTNYVLVIPEV 232 Anabaena variab...
AAN50389     162 ILFAEKRGstwSFENLVELSGYVMPGAPPR---FThETSWIGTIADAFLLFFAPLSCSFAEIEp----SRGTWCILIPEL 234 Leptospira inte...
P38586       196 AWQSVLEA---LEVGSTSLASWAYPGAAERhigVR-VTKVEYTAAEALCACFALVGCVSYKLP-----QLRGGAFVALAP 266 Myxococcus xant...

EAW36791     234 TNLESYALQRLELnHLSYQELYVTGTGDAGLKSLYYLATSQTTDp--NKIQKCKVIVYGTFTWSKQQKVR-GDVKLIKST 310 Lyngbya sp. PCC...
jgi:Ava_3491 233 IDLELYAHFLWCLgNLDYKHFHVSSLGDAGLKFLNYKTTQMPTS---NFLKRCQIIFFSTKAWSEQQKTR-AEIAIIELN 308 Anabaena variab...
AAN50389     235 EDLETFERFRRDY-EVNTINMFAGGPGDAALRYLTEMDLTGNKKd--FSPNGCEVYVIGKVAWNKKQQVR-RLMMRIHPT 310 Leptospira inte...
P38586       267 TNLVRFAELRPGLtPKRLRDVAVAGASDAVLAAQLVMAQEAGKKrlgAVLGTTEAVALRQMPWNAQQKIRgAVVRQDAVL 346 Myxococcus xant...

EAW36791     311 VAVNHHYQLIHHLFPN-RAVK 330 Lyngbya sp. PCC 8106
jgi:Ava_3491 309 SSVNYLYKLSCICFPEcQIVL 329 Anabaena variabilis ATCC 29413
AAN50389     311 EKNFRIYKKMRGIFQNkIHLK 331 Leptospira interrogans serovar Lai str. 56601
P38586       347 EEVLDRYEAAAAALPHtLRVR 367 Myxococcus xanthus DK 1622
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